We combine continuous and discontinuous Galerkin methods in the setting of a model diffusion problem. Starting from a hybrid discontinuous formulation, we replace element interiors by more general subsets of the computational domain - groups of elements that support a piecewise-polynomial continuous expansion. This step allows us to identify a~new ...
Background: People with dementia often require full-time caregivers especially in the later stages of their condition. People with dementia and caregivers’ access to reliable information on dementia is essential as it may have an important impact on patient care and quality of life. This study aims to provide an overview of the information needs an...
Published in Seminars in cell & developmental biology
NF-κB plays a pivotal role in oncogenesis. This transcription factor is best known for promoting cancer cell survival and tumour-driving inflammation. However, several lines of evidence support a crucial role for NF-κB in governing energy homeostasis and mediating cancer metabolic reprogramming. Mitochondria are central players in many metabolic pr...
Background and aims: The etiology of necrotizing enterocolitis (NEC) is unclear and postulated as being multifactorial. It has been suggested that one causative factor is the transfusion of packed red blood cells (PRBCs) leading to the disease entity commonly referred to as transfusion-associated NEC (TANEC). TANEC has been reported in North Americ...
The files contain the MINLP formulations presented in this publication. The MINLP problems are implemented and solved in GAMS version 28.2.0, using SBB, a local branch-&-bound MINLP solver. / The files contain the MINLP formulations presented in this publication. The MINLP problems are implemented and solved in GAMS version 28.2.0, using SBB, a loc...
The number of developed methodologies for the ring expansion of cyclobutanol rings to five, six and seven-membered rings has increased significantly over the last six years. In this timeframe, the semipinacol rearrangement of vinyl-group containing cyclobutanols to cyclopentanones has been advanced under photoredox and electrochemical conditions, e...
In this work, we design, prototype, test and analyse the first high-performance Herringbone-Bouligand microstructure (with Carbon Fibre Reinforced Plastic (CFRP)) inspired to the high-impact-resistant mantis shrimp's dactyl club. To this end, we devised the first prototyping procedure to manufacture point-by-point tailorable Herringbone-Bouligand C...
Published in Journal of High Energy Physics
The production of ϒ(nS) mesons (n = 1, 2, 3) in pPb and Pbp collisions at a centre-of-mass energy per nucleon pair sNN=8.16\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document...
Motivation Approximate Bayesian computation (ABC) is an important framework within which to infer the structure and parameters of a systems biology model. It is especially suitable for biological systems with stochastic and nonlinear dynamics, for which the likelihood functions are intractable. However, the associated computational cost often limit...
