The Coming of Age of Solar and Wind Power
Modeling present and future climate risk of dengue outbreak, a case study in New Caledonia
Published in Environmental Health
BackgroundDengue dynamics result from the complex interactions between the virus, the host and the vector, all being under the influence of the environment. Several studies explored the link between weather and dengue dynamics and some investigated the impact of climate change on these dynamics. Most attempted to predict incidence rate at a country...
Metformin sensitizes leukemic cells to cytotoxic lymphocytes by increasing expression of intercellular adhesion molecule...
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Published in Scientific Reports
Solid tumor cells have an altered metabolism that can protect them from cytotoxic lymphocytes. The anti-diabetic drug metformin modifies tumor cell metabolism and several clinical trials are testing its effectiveness for the treatment of solid cancers. The use of metformin in hematologic cancers has received much less attention, although allogeneic...
Non-proteolytic ubiquitylation in cellular signaling and human disease
Published in Communications Biology
Evanthia Pangou and co-authors review recent insights into the important roles of non-proteolytic ubiquitylation in cellular signaling as well as in physiology and disease.
Higher order interactions destroy phase transitions in Deffuant opinion dynamics model
Published in Communications Physics
While the Deffuant-Weisbuch model, one of the paradigmatic models of opinion dynamics, represents homophily through pairwise interactions, many real world interactions are not pairwise but happen in groups. Here, the authors take a numerical approach and extend the Deffuant model to hypergraphs of different topology, and show how introducing higher...
Use of the proteomic tool MALDI-TOF MS in termite identification
Published in Scientific Reports
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-TOF MS) has proved effective for the identification of many arthropods. A total of 432 termite specimens were collected in Mali, Cote d’Ivoire, Togo, Senegal, Switzerland and France. Morphologically, 22 species were identified, including Ancistrotermes cavithorax, Amitermes evunci...
Super-efficient drilling of metals with ultrafast non diffractive laser beams
Published in Scientific Reports
A highly efficient drilling process is found in non-transparent metallic materials enabled by the use of non-diffractive ultrafast Bessel beams. Applied for deep drilling through a 200 μm-thick steel plate, the Bessel beam demonstrates twofold higher drilling efficiency compared to a Gaussian beam of similar fluence and spot size. Notwithstanding t...
Human MuStem cells repress T-cell proliferation and cytotoxicity through both paracrine and contact-dependent pathways
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Published in Stem Cell Research & Therapy
BackgroundMuscular dystrophies (MDs) are inherited diseases in which a dysregulation of the immune response exacerbates disease severity and are characterized by infiltration of various immune cell types leading to muscle inflammation, fiber necrosis and fibrosis. Immunosuppressive properties have been attributed to mesenchymal stem cells (MSCs) th...
Intratumoural spatial distribution of S100B + folliculostellate cells is associated with proliferation and expression of...
Published in Acta Neuropathologica Communications
Folliculostellate cells are S100B-expressing cells with numerous functions in the normal anterior pituitary. These cells have also been identified in pituitary neuroendocrine tumours (PitNETs), where their precise role remains elusive. Here, we aimed to build a refined cartography of S100B-expressing cells to characterise their interpatient and int...
Differences in caecal microbiota composition and Salmonella carriage between experimentally infected inbred lines of chi...
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Published in Genetics Selection Evolution
BackgroundSalmonella Enteritidis (SE) is one of the major causes of human foodborne intoxication resulting from consumption of contaminated poultry products. Genetic selection of animals that are more resistant to Salmonella carriage and modulation of the gut microbiota are two promising ways to decrease individual Salmonella carriage. The aims of ...
