Published in Journal of developmental biology
Human eye development is coordinated through an extensive network of genetic signalling pathways. Disruption of key regulatory genes in the early stages of eye development can result in aborted eye formation, resulting in an absent eye (anophthalmia) or a small underdeveloped eye (microphthalmia) phenotype. Anophthalmia and microphthalmia (AM) are ...
Neuroinflammation is a common feature shared by neurodegenerative disorders, such as Parkinson's disease (PD), and seems to play a key role in their development and progression. Microglia cells, the principal orchestrators of neuroinflammation, can be polarized in different phenotypes, which means they are able to have anti-inflammatory, pro-inflam...
A Markov tree is a probabilistic graphical model for a random vector by which conditional independence relations between variables are encoded via an undirected tree and each node corresponds to a variable. One possible max-stable attractor for such a model is a Hüsler–Reiss extreme value distribution whose variogram matrix inherits its structure f...
Uterine fluid is an aqueous milieu to which sperm are exposed during their storage and ascent. In this study a bottom up proteomic strategy and bioinformatic analysis of hen uterine fluid was performed to improve understanding of this fluid and its potential role in sperm survival mechanisms. The proteomic data were submitted to ProteomeXchange. Am...
Whole genome duplications (WGD) have major impacts on the evolution of species, as they produce new gene copies contributing substantially to adaptation, isolation, phenotypic robustness, and evolvability. They result in large, complex gene families with recurrent gene losses in descendant species that sequence-based phylogenetic methods fail to re...
BACKGROUND: The holistic view of bacterial symbiosis, incorporating both host and microbial environment, constitutes a major conceptual shift in studies deciphering host-microbe interactions. Interactions between Steinernema entomopathogenic nematodes and their bacterial symbionts, Xenorhabdus, have long been considered monoxenic two partner associ...
Grasslands offer many environmental and economic advantages that put them at the heart of future sustainable ruminant production systems. This study aimed to quantify and map the dry matter yield (DMY) and nitrogen yield (NY) of French grasslands resulting from cutting and grazing practices, based on the existing diversity of grassland vegetation, ...
Catch-and-release (C&R) could be an interesting management tool in recreational fisheries as long as mortality remains low and the anglers’ well-being does not drop. We used a choice experiment to examine the potential of C&R angling as a monitoring tool for the salmon recreational fishery in Brittany (France). Anglers were asked to choose between ...
