High resolution imaging of molecules at the cell-substrate interface is required for understanding key biological processes. Here we propose a complete pipeline for multi-angle total internal reflection fluorescence microscopy (MA-TIRF) going from instrument design and calibration procedures to numerical reconstruction. Our custom setup is endowed ...
The ventro-intermediate nucleus (Vim), as part of the motor thalamic nuclei, is a commonly used target in functional stereotactic neurosurgery for treatment of drug-resistant tremor. As it cannot be directly visualized on routinely used magnetic resonance imaging (MRI), its clinical targeting is performed using indirect methods. Recent literature s...
Background The gut microbiome is an important determinant of human health. Its composition has been shown to be influenced by multiple environmental factors and likely by host genetic variation. In the framework of the Milieu Interieur Consortium, a total of 1000 healthy individuals of western European ancestry, with a 1:1 sex ratio and evenly stra...
Developmental cell death plays an important role in the construction of functional neural circuits. In vertebrates, the canonical view proposes a selection of the surviving neurons through stochastic competition for target-derived neurotrophic signals, implying an equal potential for neurons to compete. Here we show an alternative cell fitness sele...
The family of two-dimensional (2D) materials grows day by day, hugely expanding the scope of possible phenomena to be explored in two dimensions, as well as the possible van der Waals (vdW) heterostructures that one can create. Such 2D materials currently cover a vast range of properties. Until recently, this family has been missing one crucial mem...
We study the band gap of finite NA=7 armchair graphene nanoribbons (7-AGNRs) on Au(111) through scanning tunneling microscopy/spectroscopy combined with density functional theory calculations. The band gap of 7-AGNRs with lengths of 8 nm and more is converged to within 50 meV of its bulk value of approximate to 2.3eV, while the band gap opens by se...
Two-dimensional (2D) flows can be controlled efficiently using spanwise "waviness," i.e., a control (e.g., wall blowing and suction or wall deformation) that is periodic in the spanwise direction. This study tackles the global linear stability of 2D flows subject to small-amplitude three-dimensional (3D) spanwise-periodic control. Building on previ...
Two dicopper (II) complexes of general formula [CuLX2](2) {L = 2, 5-diphenyl-3, 4(2-pyridyl) cyclopenta-2, 4-dien-1-one, X = Cl (1) or Br (2)} have been synthesized and characterized by elemental analysis, IR, UV-Vis spectroscopic methods. The crystal structures of both complexes have been determined by single-crystal X-ray diffraction; 1 and 2 hav...
Visual crowding is the inability to perceive elements within clutter. Traditional crowding models, such as pooling, predict that performance deteriorates when flankers are added. However, this prediction has been disproved. For example, performance was found to deteriorate when a Vernier was surrounded by a single square but also to improve when mo...
