Introduction Artemisinin-based combination therapies (ACTs) are the first-line antimalarial drugs used to treat uncomplicated Plasmodium falciparum alaria in many endemic countries worldwide. The present work reviewed the therapeutic efficacy of ACT in Cameroon more than 10 years after the initial change in national drug policy in 2004.Methods A Pu...
We present a dynamic rupture model of the 2016 M-w 7.8 Kaikoura earthquake to unravel the event's riddles in a physics-based manner and provide insight on the mechanical viability of competing hypotheses proposed to explain them. Our model reproduces key characteristics of the event and constraints puzzling features inferred from high-quality obser...
The study of small reservoirs with low suspended sediment concentration (CSS) is still a challenge for remote sensing. In this work we estimate CSS from the optical properties of water and orbital imagery. Campaigns were carried out at selected dates according to the calendar of sensor passages, rainfall seasonality and hydrograph of the reservoir ...
La gestion et le maintien de la fertilité des sols ont été toujours une préoccupation majeure dans les exploitations agricoles en zone sahélienne. Certaines pratiques paysannes comme la mobilité périodique de l'habitat à l'intérieur des champs constituent un moyen pour restaurer les sols dégradés dans l'Ouest nigérien. Ce travail vise à étudier l'e...
En zone soudanienne, les cultures sont pratiquées depuis des siècles par les populations rurales sous forme d'agroforesterie. Cette pratique est dominée par les parcs à karités (Vitellaria paradoxa), en alternance avec les jachères dans lesquelles les arbres se régénèrent. Pour évaluer les possibilités de densification en karité de ces parcs, nous ...
Ocean boundary current systems are key components of the climate system, are home to highly productive ecosystems, and have numerous societal impacts. Establishment of a global network of boundary current observing systems is a critical part of ongoing development of the Global Ocean Observing System. The characteristics of boundary current systems...
Over the past few decades, treatment of multidrug-resistant (MDR)/ extensively drugresistant (XDR) tuberculosis (TB) has been challenging because of its prolonged duration (up to 2024 months), toxicity, costs and sub-optimal outcomes. After over 40 years of neglect, two new drugs (bedaquiline and delamanid) have been made available to manage diffic...
Toxoplasma gondii is a zoonotic protozoan with a worldwide occurrence, but the determinants of the current pattern in the geographical distribution of T. gondii lineages and strains remain poorly understood. To test the influence of human trade on T. gondii populations, we conducted a population genetic study of 72 T. gondii animal isolates from Se...
The tribe Geonomateae is a widely distributed group of 103 species of Neotropical palms which contains six ecologically important understory or subcanopy genera. Although it has been the focus of many studies, our understanding of the evolutionary history of this group, and in particular of the taxonomically complex genus Geonoma, is far from compl...
The polyketide, 6-pentyl-alpha-pyrone (6-PP), has a characteristic coconut aroma and is produced by many Trichoderma species. In this study, we screened formerly isolated Trichoderma strains for 6-PP production grown using solid-state fermentation (SSF). Sugarcane bagasse supplemented with a nutrient solution was used as the support material for th...
