International Journal of Dermatology
Background We previously described a new variant of endemic pemphigus foliaceus in El Bagre, Colombia (El Bagre-EPF).
Clinical and Experimental Dermatology
We identified a new variant of endemic pemphigus foliaceus in El Bagre, Colombia, South America, which we term El Bagre-EPF, and observed reactivity to arrector pili muscle (APM), thus we tested for autoimmunity to APM.
We took skin biopsies from 30 patients with El Bagre-EPF and 30 healthy controls (HCs) matched by age,...
Alcoholism Clinical and Experimental Research
Our findings demonstrate for the first time that blockade of NOP receptors attenuates ethanol self-administration and ethanol-motivated behaviors, stress-induced ethanol seeking, and ethanol-induced stimulation of brain reward pathways in lines of rats that exhibit excessive ethanol consumption. Results suggest that LY2940094 may have potential the...
Uncoordinated 119 protein (UNC119) is a partner of transducin-α subunit (Gαt ) that is essential for transducin trafficking in rod photoreceptors. The interaction is known to involve binding of the acylated N terminus of Gαt to the hydrophobic pocket of UNC119. To gain insights into the mechanism of transducin trafficking, we isolated a highly pure...
Journal of Cutaneous Pathology
Background: Melanin and melanophages are commonly seen under the basement membrane zone of the skin in patients affected by a new variant of endemic pemphigus foliaceus in El Bagre, Colombia (El Bagre‐EPF).
Objective: Our study was conducted to determine the nature of these pigmentary alterations.
Methods: We utilized clinical, histopathologi...