Published in Nature Communications
Nebulin-based nemaline myopathy is a heterogenous disease with unclear pathological mechanisms. Here, the authors generate a mouse model that mimics the most common genetic cause of the disease and demonstrate that muscle weakness in this model is associated with twisted actin filaments and altered tropomyosin and troponin behaviour.
Published in Scientometrics
The interdisciplinary nature of library and information science (LIS) research has been highlighted for some time now. The term “interdisciplinary” is used primarily in the LIS literature as a general concept with different meanings that refer either to the coexistence of researchers from different scientific fields or to cross-disciplinary collabo...
Published in Environmental Science and Pollution Research
This case-control study aimed to investigate the relationship of indoor radon gas concentration and residential building characteristics with mental health with multiple sclerosis (MS) in Yazd City, Iran. The participants included 45 patients with MS and 100 healthy individuals. The participants’ socio-economic status and residential building chara...
Published in Scientific Data
Measurement(s) imaging assay • head and neck squamous cell carcinomaTechnology Type(s)magnetic resonance imagingFactor Type(s)contrast agentSample Characteristic - OrganismHomo sapiens Machine-accessible metadata file describing the reported data: 10.6084/m9.figshare.11409516
Published in Nature Communications
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Published in Environmental Science and Pollution Research
Published in Scientific Reports
Androgen signalling is a critical driver of male development. Fetal steroid signalling can be dysregulated by a range of environmental insults and clinical conditions. We hypothesised that poor adult male health was partially attributable to aberrant androgen exposure during development. Testosterone was directly administered to developing male ovi...
Published in Nature Communications
The cerebellum is critical in sensory-motor control and is structurally diverse across vertebrates. Here, the authors investigate the evolutionary relationship between locomotory mode and cerebellum architecture across squamates by integrating study of gene expression, cell distribution, and 3D morphology.
Published in Nature Communications
Oncogenic exosomes can circulate in the blood, but their selective removal has not been possible. Here the authors show that aptamer-functionalised mesoporous silica nanoparticles can find to a specific population of circulating exosomes and eliminate them via the hepatobiliary route.
Published in Scientific Reports
Limb-girdle muscular dystrophy type 2D (LGMD2D) is characterized by a progressive proximal muscle weakness. LGMD2D is caused by mutations in the gene encoding α-sarcoglycan (α-SG), a dystrophin-associated glycoprotein that plays a key role in the maintenance of sarcolemma integrity in striated muscles. We report here on the development of a new in ...
