Impact of inactivated COVID-19 vaccines on viral shedding in B.1.617.2 (Delta) variant-infected patients.
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Published in Science China. Life sciences
Published in Science China. Life sciences
Published in Science China. Life sciences
Enterovirus A71 (EV-A71) causes major outbreaks of hand, foot, and mouth disease (HFMD) in many countries, most frequently affecting children, and a small proportion of cases may lead to death. Currently, no vaccine is available in most endemic regions, and no licenced treatments for EV-A71 infection are available. Here, we characterize a human mon...
Published in Science China. Life sciences
Published in Science China. Life sciences
Published in Science China. Life sciences
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is characterized by a strong production of inflammatory cytokines such as TNF and IL-6, which underlie the severity of the disease. However, the molecular mechanisms responsible for such a strong immune response remains unclear. Here, utiliz...
Published in Science China. Life sciences
Published in Science China Physics, Mechanics & Astronomy
Searching for compact objects (black holes, neutron stars, or white dwarfs) in the Milky Way is essential for understanding the stellar evolution history, the physics of compact objects, and the structure of our Galaxy. Compact objects in binaries with a luminous stellar companion are perfect targets for optical observations. Candidate compact obje...
Published in Science China. Life sciences
Published in Science China. Life sciences
Published in Science China. Life sciences
Signaling pathway alterations in COVID-19 of living humans as well as therapeutic targets of the host proteins are not clear. We analyzed 317 urine proteomes, including 86 COVID-19, 55 pneumonia and 176 healthy controls, and identified specific RNA virus detector protein DDX58/RIG-I only in COVID-19 samples. Comparison of the COVID-19 urinary prote...