7 Fragen an Dr. Corinna Kosnopfel
Published in Kompass Onkologie
CLL: Einblicke in aktuelle Entwicklungen der Behandlung
Published in Kompass Onkologie
4-Jahres-Update der Murano-Studie bestätigt den Stellenwert von Venetoclax in der 2. Therapielinie der CLL
Published in Kompass Onkologie
Purpose: In previous analyses of the MURANO study, fixed-duration venetoclax plus rituximab (VenR) resulted in improved progression-free survival (PFS) compared with bendamustine plus rituximab (BR) in patients with relapsed or refractory chronic lymphocytic leukemia (CLL). At the 4-year follow-up, we report long-term outcomes, response to subseque...
Meditation in Complementary and Integrative Medicine: Taxonomy of Effects and Methods
Published in Complementary Medicine Research
CLL: Wie die Therapie den Verlauf einer COVID-19 Infektion beeinflusst
Published in Kompass Onkologie
Die Chemo-Immuntherapie ist der Standard in der Erstlinienbehandlung von CLL-Patienten ohne del17p- oder TP 53-Mutation; körperlich fitte Patienten werden mit Fludarabin, Cyclophosphamid und Rituximab (FCR)1 behandelt. Aufgrund des hohen Risikos von schweren Neutropenien und Infektionen mit FCR muss bei Patienten im Alter von >65 Jahren Bendamustin...
Book Review
Published in Complementary Medicine Research
Hochrisiko-CLL: Zielgerichtete Kombinationstherapie verbessert das Überleben
Published in Kompass Onkologie
Background: Patients with chronic lymphocytic leukaemia and high-risk features have poorer outcomes on ibrutinib than those without high-risk features. The aim of this study was to assess the benefit of adding ublituximab, an anti-CD20 monoclonal antibody, to ibrutinib therapy in this population. Methods: We did a randomised, phase 3, multicentre s...
Detectable SARS-CoV-2 RNAemia in Critically Ill Patients, but Not in Mild and Asymptomatic Infections
...Published in Transfusion Medicine and Hemotherapy
Background: The SARS-CoV-2 pandemic has challenged many of our current routine practices in the treatment and care of patients. Given the critical importance of blood donation and transfusion we analyzed 92 blood samples of individuals infected with SARS-CoV-2 stratified by symptoms. Study Design and Methods: We therefore tested blood samples for S...
Neue Ansätze für die Glaukombehandlung
Published in Kompass Ophthalmologie
The Impact of Platinum-Containing Chemotherapies in Advanced Triple-Negative Breast Cancer: Meta-Analytical Approach to ...
Published in Oncology Research and Treatment
Background: Triple-negative breast cancer (TNBC), the most common type of breast cancer, is associated with poor patient prognosis. Platinum-containing chemotherapies are commonly used in the treatment and prevention of advanced TNBC. Objectives and Methods: To systematically evaluate the effectiveness and safety of platinum-containing chemotherapi...
