Motor origin of temporal predictions in auditory attention
Published in Proceedings of the National Academy of Sciences
Unique structural features of the AIPL1–FKBP domain that support prenyl lipid binding and underlie protein malfunction i...
Published in Proceedings of the National Academy of Sciences
Automated glycan assembly using the Glyconeer 2.1 synthesizer
Published in Proceedings of the National Academy of Sciences
Real-time analysis of RAG complex activity in V(D)J recombination.
Published in Proceedings of the National Academy of Sciences
Single-molecule FRET (smFRET) and single-molecule colocalization (smCL) assays have allowed us to observe the recombination-activating gene (RAG) complex reaction mechanism in real time. Our smFRET data have revealed distinct bending modes at recombination signal sequence (RSS)-conserved regions before nicking and synapsis. We show that high mobili...
Parent-of-origin effects of A1CF and AGO2 on testicular germ-cell tumors, testicular abnormalities, and fertilization bi...
Published in Proceedings of the National Academy of Sciences
Testicular tumors, the most common cancer in young men, arise from abnormalities in germ cells during fetal development. Unconventional inheritance for testicular germ cell tumor (TGCT) risk both in humans and mice implicates epigenetic mechanisms. Apolipoprotein B mRNA-editing enzyme complex 1 (APOBEC1) cytidine deaminase and Deadend-1, which are ...
Hostile attributional bias and aggressive behavior in global context.
...Published in Proceedings of the National Academy of Sciences
We tested a model that children's tendency to attribute hostile intent to others in response to provocation is a key psychological process that statistically accounts for individual differences in reactive aggressive behavior and that this mechanism contributes to global group differences in children's chronic aggressive behavior problems. Particip...
The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea.
Published in Proceedings of the National Academy of Sciences
Proper tissue development requires strict coordination of proliferation, growth, and differentiation. Strict coordination is particularly important for the auditory sensory epithelium, where deviations from the normal spatial and temporal pattern of auditory progenitor cell (prosensory cell) proliferation and differentiation result in abnormal cell...
An estimate of the number of tropical tree species.
...Published in Proceedings of the National Academy of Sciences
The high species richness of tropical forests has long been recognized, yet there remains substantial uncertainty regarding the actual number of tropical tree species. Using a pantropical tree inventory database from closed canopy forests, consisting of 657,630 trees belonging to 11,371 species, we use a fitted value of Fisher's alpha and an approx...
The spontaneous emergence of conventions: an experimental study of cultural evolution.
Published in Proceedings of the National Academy of Sciences
How do shared conventions emerge in complex decentralized social systems? This question engages fields as diverse as linguistics, sociology, and cognitive science. Previous empirical attempts to solve this puzzle all presuppose that formal or informal institutions, such as incentives for global agreement, coordinated leadership, or aggregated infor...
TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival...
...Published in Proceedings of the National Academy of Sciences
Transient receptor potential vanilloid subfamily member 6 (TRPV6) is a highly selective calcium channel that has been considered as a part of store-operated calcium entry (SOCE). Despite its first discovery in the early 2000s, the role of this channel in prostate cancer (PCa) remained, until now, obscure. Here we show that TRPV6 mediates calcium en...
