Published in Biochemistry. Biokhimiia
Aminoacyl-RNA synthetases (aaRSs) are among the key enzymes of protein biosynthesis. They are responsible for conducting the first step in the protein biosynthesis, namely attaching amino acids to the corresponding tRNA molecules both in cytoplasm and mitochondria. More and more research demonstrates that mutations in the genes encoding aaRSs lead ...
Published in Biochemistry. Biokhimiia
Many viruses, beside binding to their main cell target, interact with other molecules that promote virus adhesion to the cell; often, these additional targets are glycans. The main receptor for SARS-CoV-2 is a peptide motif in the ACE2 protein. We studied interaction of the recombinant SARS-CoV-2 spike (S) protein with an array of glycoconjugates, ...
Published in Biochemistry. Biokhimiia
Mycobacterium tuberculosis possesses a significant arsenal of strategies to combat immune defense of the host organism. Small noncoding RNAs, which constitute the largest group of regulatory RNAs, play an important role in the host–pathogen interactions and represent one of the levels of the regulation of interactions of microbial cells with their ...
Published in Biochemistry (Moscow) Supplement. Series A, Membrane and Cell Biology
The COVID-19 pandemic has swept the world and required the mobilization of scientists and clinicians around the world to combat this serious disease. Along with SARS-CoV-2 virology research, understanding of the fundamental physiological processes, molecular and cellular mechanisms and intracellular signaling pathways underlying the clinical manife...
Published in Studies on Russian Economic Development
The article analyzes the level of import dependence of Russian industry in relation to the supply of intermediate consumption products from China and in general from all countries of the world. The study was carried out during the period of the increasing spread of coronavirus infection in order to determine the industries that are potentially the ...
Published in Journal of Computer and Systems Sciences International
We consider a methodology for organizing hybrid computing structures to simulate abrupt changes in controlled natural processes and analyzing phases of extreme environmental phenomena. Systems of differential equations with the dynamically redefinable right-hand side at special moments (events) are used. The truth conditions for transitions are obt...
Published in Studies on Russian Economic Development
The article, which is a continuation of the study published in the previous issue of the journal, describes a methodology for assessing the total cost of labor in the economy in the context of certain groups of the employed population. In particular, the analysis of estimates of direct and indirect labor costs for three levels of qualifications of ...
Published in Studies on Russian Economic Development
The paper analyzes and comments on the results of a regular survey of Russian enterprises in the real sector, which was conducted by the Institute of National Economic Forecasting of the Russian Academy of Sciences. Information on the impact of the coronavirus pandemic on the activities of domestic enterprises is provided. The paper presents the op...
Published in Studies on Russian Economic Development
Based on the modified Okun’s model, the article evaluates the impact of changes in production volumes on the dynamics of unemployment in Russia and three regional clusters differing in the unemployment rate and behavioral responses to economic shocks. Assessing the specifications of the basic Okun model on the data of 2010–2020 made it possible to ...
Published in Studies on Russian Economic Development
Could the forced digitalization of multiple spheres of human life caused by the coronavirus pandemic lead to radical changes in the global and Russian economies? How and to what extent have ubiquitous lockdowns affected the digital transformation? The new model of the digital economy growth, formed during the ongoing crisis, actually contributes to...
