Hucke, Anna Park, Ga Young Bauer, Oliver B. Beyer, Georg Köppen, Christina Zeeh, Dorothea Wehe, Christoph A. Sperling, Michael Schröter, Rita Kantauskaitè, Marta
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Published in
Frontiers in Chemistry
Cancer treatment with platinum compounds is an important achievement of modern chemotherapy. However, despite the beneficial effects, the clinical impact of these agents is hampered by the development of drug resistance as well as dose-limiting side effects. The efficacy but also side effects of platinum complexes can be mediated by uptake through ...
Lin, Chiung-Tsung Lu, Jang-Jih Chen, Yu-Ching Kok, Victor C Horng, Jorng-Tzong
Published in
PeerJ
Few studies compared the diagnostic value of procalcitonin with a combination of other tests including lactate and high-sensitivity C-reactive protein in the prediction of pathogenic bacteremia in emergency department adult patients. We performed a retrospective study assessing the differences in performances of procalcitonin at a cutoff of 0.5 ng/...
González-Chang, Mauricio Boyer, Stéphane Lefort, Marie-Caroline Nboyine, Jerry Wratten, Steve D
Published in
PeerJ
Melolonthinae beetles, comprising different white grub species, are a globally-distributed pest group. Their larvae feed on roots of several crop and forestry species, and adults can cause severe defoliation. In New Zealand, the endemic scarab pest Costelytra zealandica (White) causes severe defoliation on different horticultural crops, including g...
Sprague R, Boyer, Stephane Stevenson GM, Wratten SD,
Published in
PeerJ
BACKGROUND:
Honeybees (Apis mellifera L.) are frequently used in agriculture for pollination services because of their abundance, generalist floral preferences, ease of management and hive transport. However, their populations are declining in many countries. Agri-Environment Schemes (AES) are being implemented in agricultural systems to combat th...
Harpinder Sandhu Benjamin Waterhouse Stephane Boyer Steve Wratten
Published in
PeerJ
Marie-Caroline Lefort Stéphane Boyer Jessica Vereijssen Rowan Sprague Travis R. Glare Susan P. Worner Stephane Boyer
Published in
PeerJ
Zhao, Mindi Li, Xundou Li, Menglin Youhe Gao
Published in
PeerJ
Urine can be a better source than blood for biomarker discovery since it accumulates many changes. The urine proteome is susceptible to many factors, including anesthesia. Pentobarbital sodium and chloral hydrate are commonly used anesthetics in animal experiments. This study demonstrated the effects of these two anesthetics on the rat urine proteo...
Börnigen, Daniela Moon, Yo Sup Rahnavard, Gholamali Waldron, Levi McIver, Lauren Shafquat, Afrah Franzosa, Eric A Miropolsky, Larissa Sweeney, Christopher Morgan, Xochitl C
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Published in
PeerJ
Modern biological research requires rapid, complex, and reproducible integration of multiple experimental results generated both internally and externally (e.g., from public repositories). Although large systematic meta-analyses are among the most effective approaches both for clinical biomarker discovery and for computational inference of biomolec...
Haroun Chenchouni Menasria, Taha Neffar, Souad Chafaa, Smail Bradai, Lyes Chaibi, Rachid Mekahlia, Mohamed Nacer Bendjoudi, Djamel Bachir, Abdelkrim Si
Published in
PeerJ
Zhang, Fanshuang Cheng, Xiaoyu Yuan, Yuan Wu, Jianqiang Youhe Gao
Published in
PeerJ
Urine accumulates traces of changes that occur in the body and can potentially serve as a better biomarker source. Urinary microRNA is a promising class of non-invasive disease biomarkers. However, long-term frozen human urine samples are not a good source for the extraction of urinary microRNA. In this paper, we demonstrate that urinary microRNA c...