Toropova, Alla. Toropov, Andrey Benfenati, Emilio Gini, Giuseppina Leszczynska, Danuta Leszczynski, Jerzy
Published in
Open Chemistry
Optimal descriptors calculated with simplified molecular input line entry system (SMILES) have been examined as a tool for prediction of anxiolytic activity. Descriptors calculated with SMILES (a) of keto-isomers; (b) of enol-isomers; and (c) of both keto-isomers together with enol-isomers have been studied. Three approaches have been compared: 1. ...
Lodhi, Tahira I. Alchalabi, Tania Yosef Meystel
Published in
Oxford Medicine Online
Tausch, Arno Grinin, Leonid Korotayev, Andrey
In 1937, the Japanese economist Kaname Akamatsu discovered specific links between the rise and decline of the global peripheries. Akamatsu's theory of development describes certain mechanisms whose working results in the narrowing of the gap between the level of development of the economy of developing and developed countries, and, thus, in the res...
Low, Ting Ting Teo, Lynette Li San Krishna Kumar, Shoban Tay, Edgar Lik Wui Yip, James Wei Lun
Published in
European Heart Journal - Cardiovascular Imaging
Rajappa-Titu, Lional Suematsu, Takuma Munoz-Tello, Paola Long, Marius Demir, Özlem Cheng, Kevin J Stagno, Jason R Luecke, Hartmut Amaro, Rommie E Aphasizheva, Inna
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Published in
Nucleic Acids Research
Terminal uridyltransferases (TUTases) execute 3' RNA uridylation across protists, fungi, metazoan and plant species. Uridylation plays a particularly prominent role in RNA processing pathways of kinetoplastid protists typified by the causative agent of African sleeping sickness, Trypanosoma brucei In mitochondria of this pathogen, most mRNAs are in...
Lowe, Todd M Chan, Patricia P
Published in
Nucleic acids research
High-throughput genome sequencing continues to grow the need for rapid, accurate genome annotation and tRNA genes constitute the largest family of essential, ever-present non-coding RNA genes. Newly developed tRNAscan-SE 2.0 has advanced the state-of-the-art methodology in tRNA gene detection and functional prediction, captured by rich new content ...
Tkachenko, Andrew Matthews, J M Aerts, Conny Pavlovski, K Pápics, P I Zwintz, K Cameron, C Walker, Gah Kuschnig, R Degroote, P
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Published in
Monthly Notices of the Royal Astronomical Society
Binary stars provide a valuable test of stellar structure and evolution, because the masses of the individual stellar components can be derived with high accuracy and in a model-independent way. In this work, we study Spica, an eccentric double-lined spectroscopic binary system with a β Cep type variable primary component. We use state-of- the-art ...
Hinrichs, Angie S Raney, Brian J Speir, Matthew L Rhead, Brooke Casper, Jonathan Karolchik, Donna Kuhn, Robert M Rosenbloom, Kate R Zweig, Ann S Haussler, David
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Published in
Bioinformatics (Oxford, England)
Supplementary data are available at Bioinformatics online.
Siwak, Michal Ogloza, Waldemar Rucinski, Slavek M Moffat, Anthony F J Matthews, Jaymie M Cameron, Chris Guenther, David B Kuschnig, Rainer Jason Rowe Sasselov, Dimitar
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Published in
Monthly Notices of the Royal Astronomical Society
Results of the time variability monitoring of the two classical T Tauri stars, RU Lup and IM Lup, are presented. Three photometric data sets were utilized:(1) simultaneous (same field) MOST satellite observations over four weeks in each of the years 2012 and 2013,(2) multicolour observations at the South African Astronomical Observatory in April– M...
McCollum, Rosalind Otiso, Lilian Mireku, Maryline Theobald, Sally de Koning, Korrie Hussein, Salim Taegtmeyer, Miriam
Published in
Health Policy and Planning
This in-depth analysis which captures multiple perspectives results in robust recommendations for strategy revision informed by the Five Wonders of Change Framework. These recommendations point towards a more people-centred health system for improved equity and effectiveness and indicate priority areas for action if success of policy change through...
