SplitStrains, a tool to identify and separate mixed Mycobacterium tuberculosis infections from WGS data.
Published in Microbial genomics
SplitStrains, a tool to identify and separate mixed Mycobacterium tuberculosis infections from WGS data.
Effect of five decontamination methods on face masks and filtering facepiece respirators contaminated with Staphylococcu...
Published in Access Microbiology
Introduction. In the context of the global pandemic due to SARS-CoV-2, procurement of personal protective equipment during the crisis was problematic. The idea of reusing and decontaminating personal surgical masks in facilities was explored in order to avoid the accumulation of waste and overcome the lack of equipment. Hypothesis. Our hypothesis i...
Successful treatment of vancomycin-resistant enterococcal infection of an external ventricular drain with 2 weeks of int...
Published in Access Microbiology
Hydrocephalus is a common condition worldwide, and is frequently managed by diversion of cerebrospinal fluid (CSF), either externally with a drain or internally with a shunt. An external ventricular drain (EVD) can be an essential treatment modality, but is associated with a risk of infection, most commonly caused by Staphylococcal species, which c...
Use of genomics to explore AMR persistence in an outdoor pig farm with low antimicrobial usage.
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Published in Microbial genomics
Food animals may be reservoirs of antimicrobial resistance (AMR) passing through the food chain, but little is known about AMR prevalence in bacteria when selective pressure from antimicrobials is low or absent. We monitored antimicrobial-resistant Escherichia coli over 1 year in a UK outdoor pig farm with low antimicrobial usage (AMU) compared to ...
Characterization of Bud3 domains sufficient for bud neck targeting in S. cerevisiae
Published in Access Microbiology
The cytoskeleton serves a diverse set of functions in both multi- and unicellular organisms, including movement, transport, morphology, cell division and cell signalling. The septin family of cytoskeletal proteins are found within all fungi and metazoans and can generate three-dimensional scaffolds in vivo that promote membrane curvature, serve as ...
An assessment of the evidence for antibacterial activity of stinging nettle ( Urtica dioica ) extracts
Published in Access Microbiology
Stinging nettles ( Urtica spp.) have been used in a diverse range of traditional and historical medicines from around the world for the treatment of skin diseases, wounds, urinary disorders, respiratory diseases, bone and joint pain, anaemia and other circulatory problems, as well as in cosmetic preparations for skin and haircare. As part of an int...
Contribution of the efflux pump AcrAB-TolC to the tolerance of chlorhexidine and other biocides in Klebsiella spp.
Published in Journal of medical microbiology
Introduction. We are becoming increasingly reliant on the effectiveness of biocides to combat the spread of Gram-negative multi-drug-resistant (MDR) pathogens, including Klebsiella pneumoniae. It has been shown that chlorhexidine exposure can lead to mutations in the efflux pump repressor regulators SmvR and RamR, but the contribution of each indiv...
Cholera outbreak: antibiofilm activity, profiling of antibiotic-resistant genes and virulence factors of toxigenic Vibri...
Published in Access Microbiology
Vibrio cholerae is a biofilm-forming pathogen with various virulence phenotypes and antimicrobial resistance traits. Phenotypic characteristics play a critical role in disease transmission and pathogenesis. The current study elucidated antibiofilm formation activity, profiled antibiotic-resistant genes and virulence factors of toxigenic Vibrio chol...
Pleuritis due to Mycobacterium xenopi without pulmonary infection
Published in Access Microbiology
Nontuberculous mycobacteria (NTM) may cause pulmonary and extra-pulmonary disease in both immunocompetent and immunocompromised patients. Pleuritis is an uncommon manifestation on NTM disease, and pleuritis caused by Mycobacterium xenopi has only been described once before. Because it is considered to be an environmental contaminant, isolation of M...
Global evolutionary dynamics and resistome analysis of Clostridioides difficile ribotype 017.
Published in Microbial genomics
