Khalil, Kasem Khan Mamun, Mohammad Mahbubur Rahman Sherif, Ahmed Elsersy, Mohamed Said Imam, Ahmad Abdel-Aliem Mahmoud, Mohamed Alsabaan, Maazen
Published in
Sensors (Basel, Switzerland)
Alzheimer's disease (AD) is a progressive illness with a slow start that lasts many years; the disease's consequences are devastating to the patient and the patient's family. If detected early, the disease's impact and prognosis can be altered significantly. Blood biosamples are often employed in simple medical testing since they are cost-effective...
Park, Don Young Olson, Thomas E Upfill-Brown, Alexander Adejuyigbe, Babapelumi Shah, Akash A Sheppard, William L Park, Cheol Wung Heo, Dong Hwa
Published in
International journal of spine surgery
Biportal spinal endoscopy is increasingly utilized for lumbar disc herniations and lumbar stenosis. The objective was to investigate the safety and effectiveness of the technique in the outpatient vs inpatient setting. This is a comparative study of consecutive patients who underwent biportal spinal endoscopy by a single surgeon at a single institu...
Shariq, Mohd Quadir, Neha Alam, Anwar Zarin, Sheeba Sheikh, Javaid A Sharma, Neha Samal, Jasmine Ahmad, Uzair Kumari, Indu Hasnain, Seyed E
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Published in
Autophagy
Intracellular pathogens have evolved various efficient molecular armaments to subvert innate defenses. Cellular ubiquitination, a normal physiological process to maintain homeostasis, is emerging one such exploited mechanism. Ubiquitin (Ub), a small protein modifier, is conjugated to diverse protein substrates to regulate many functions. Structural...
Published in
Virulence
Edwardsiella piscicida is an Enterobacteriaceae that is abundant in water and causes food and waterborne infections in fish, animals, and humans. The bacterium causes Edwardsiellosis in farmed fish and can lead to severe economic losses in aquaculture worldwide. E. piscicida is an intracellular pathogen that can also cause systemic infection. Type ...
Eisenberg, Tobias Abdellatif, Mahmoud Zimmermann, Andreas Schroeder, Sabrina Pendl, Tobias Harger, Alexandra Stekovic, Slaven Schipke, Julia Magnes, Christoph Schmidt, Albrecht
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Published in
Autophagy
Pol, Jonathan Buqué, Aitziber Aranda, Fernando Bloy, Norma Cremer, Isabelle Eggermont, Alexander Erbs, Philippe Fucikova, Jitka Galon, Jérôme Limacher, Jean-Marc
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Published in
Oncoimmunology
Oncolytic virotherapy relies on the administration of non-pathogenic viral strains that selectively infect and kill malignant cells while favoring the elicitation of a therapeutically relevant tumor-targeting immune response. During the past few years, great efforts have been dedicated to the development of oncolytic viruses with improved specifici...
Nakajima, Ken-Ichi Zhao, Min
Published in
Channels (Austin, Tex.)
Ladoire, Sylvain Senovilla, Laura Enot, David Ghiringhelli, François Poirier-Colame, Vichnou Chaba, Kariman Erdag, Gulsun Schaefer, Jochen T. Deacon, Donna H. Zitvogel, Laurence
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Published in
OncoImmunology
Melanoma is known to be under latent immunosurveillance. Here, we studied four biomarkers of immunogenic cell stress and death (microtubule-associated proteins 1A/1B light chain 3B (MAP-LC3B, best known as LC3B)-positive puncta in the cytoplasm as a sign of autophagy; presence of nuclear HMGB1; phosphorylation of eIF2 alpha; increase in ploidy) in ...
Ladoire, Sylvain Enot, David Andre, Fabrice Zitvogel, Laurence Guido Kroemer
Published in
OncoImmunology
It is well established that the anticancer immune response determines the success of anthracycline-based adjuvant chemotherapy of breast cancer. This effect is in part due to the capacity of anthracyclines to induce immunogenic cell death (ICD), a cell death modality that is preceded by autophagy and followed by HMGB1 release. Recent data on 1,798 ...
Sedlik, Christine Heitzmann, Adèle Viel, Sophie Ait Sarkouh, Rafik Batisse, Cornélie Schmidt, Frédéric De La Rochere, Philippe Amzallag, Nathalie Osinaga, Eduardo Oppezzo, Pablo
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Published in
OncoImmunology
