Mulaudzi, Fhumulani Mavis Anokwuru, Rafiat Ajoke Du-Plessis, Moselene A. R. Lebese, Rachael T.
Published in
Frontiers in Sociology
Caregiving is a prominent concept in the Ubuntu philosophy, and caring and visitation of the sick is regarded as an example of Ubuntu. The restrictive visitation policy adopted in the hospitals during the coronavirus disease 2019 (COVID-19) pandemic affected the exhibition of this concept among patients, nurses, and families. The narrative inquiry ...
Khot, Varada Zorz, Jackie Gittins, Daniel A. Chakraborty, Anirban Bell, Emma Bautista, María A. Paquette, Alexandre J. Hawley, Alyse K. Novotnik, Breda Hubert, Casey R. J.
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Published in
Frontiers in Microbiology
Many pathways for hydrocarbon degradation have been discovered, yet there are no dedicated tools to identify and predict the hydrocarbon degradation potential of microbial genomes and metagenomes. Here we present the Calgary approach to ANnoTating HYDrocarbon degradation genes (CANT-HYD), a database of 37 HMMs of marker genes involved in anaerobic ...
Wrońska, Anna Katarzyna Kaczmarek, Agata Kazek, Michalina Boguś, Mieczysława Irena
Published in
Frontiers in Physiology
Apoptosis and autophagy, the mechanisms of programmed cell death, play critical roles in physiological and pathological processes in both vertebrates and invertebrates. Apoptosis is also known to play an important role in the immune response, particularly in the context of entomopathogenic infection. Of the factors influencing the apoptotic process...
Chen, Zuhua Yuan, Jiajia Xu, Yingying Zhang, Cheng Li, Zhongwu Gong, Jifang Li, Yanyan Shen, Lin Gao, Jing
Published in
Frontiers in Pharmacology
RC48-ADC is a novel humanized antibody specific for human epidermal growth factor receptor 2 (HER2)in conjugation with a microtubule inhibitor via a cleavable linker. This study was to evaluate the antitumor activity and mechanism of RC48-ADC in gastric cancer (GC) and explore the population that may benefit from RC48-ADC treatment. Four human GC c...
Zhu, Changliang Wang, Lei Ding, Jiangwei Li, Hailiang Wan, Din Sun, Yangyang Guo, Baorui He, Zhenquan Ren, Xiaofan Jiang, Shucai
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Published in
Frontiers in Behavioral Neuroscience
A high percentage of relapse to compulsive cocaine-taking and cocaine-seeking behaviors following abstinence constitutes a major obstacle to the clinical treatment of cocaine addiction. Thus, there is a substantial need to develop effective pharmacotherapies for the prevention of cocaine relapse. The reinstatement paradigm is known as the most comm...
Sichting, Freddy Kram, Nicolai C. Legerlotz, Kirsten
Published in
Frontiers in Physiology
Achilles tendon adaptation is a key aspect of exercise performance and injury risk prevention. However, much debate exists about the adaptation of the Achilles tendon in response to exercise activities. Most published research is currently limited to elite athletes and selected exercise activities. Also, existing studies on tendon adaptation do not...
Lew, Bob Kõlves, Kairi Lester, David Chen, Won Sun Ibrahim, Nurashikin bt Khamal, Noor Raihan bt Mustapha, Feisul Chan, Caryn Mei Hsien Ibrahim, Norhayati Siau, Ching Sin
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Published in
Frontiers in Psychiatry
Background: Suicide is a preventable cause of death. Examining suicide rates and trends are important in shaping national suicide prevention strategies. Therefore, the objectives of this study were to analyze age-standardized suicide trends of Malaysia between 2000 and 2019 using the WHO Global Health Estimates data, and to compare the 2019 rate wi...
Cao, Yudong Zhu, Hecheng Liu, Weidong Wang, Lei Yin, Wen Tan, Jun Zhou, Quanwei Xin, Zhaoqi Huang, Hailong Xie, Dongcheng
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Published in
Frontiers in Genetics
Background: Lower-grade gliomas (LGGs) are a heterogeneous set of gliomas. One of the primary sources of glioma heterogeneity is genomic instability, a novel characteristic of cancer. It has been reported that long noncoding RNAs (lncRNAs) play an essential role in regulating genomic stability. However, the potential relationship between genomic in...
Reimann, Mareike Peters, Eileen Diewald, Martin
Published in
Frontiers in Sociology
The COVID-19 pandemic has dramatically affected everyone’s daily life in one way or another, requiring a re-negotiation of existing strategies for work–life integration, not only for individuals but also within families and partnerships. To contribute to existing knowledge on work-life integration during COVID-19 in Germany, we look at gender and p...
Agostinho, Daniel Caramelo, Francisco Moreira, Ana Paula Santana, Isabel Abrunhosa, Antero Castelo-Branco, Miguel
Published in
Frontiers in Neuroscience
Background: In recent years, classification frameworks using imaging data have shown that multimodal classification methods perform favorably over the use of a single imaging modality for the diagnosis of Alzheimer’s Disease. The currently used clinical approach often emphasizes the use of qualitative MRI and/or PET data for clinical diagnosis. Bas...
