Li, Xiao Li, Yize Bai, Shuang Zhang, Jing Liu, Zhengcai Yang, Jingyue
Published in
Cancer Management and Research
Background Hypoxia is an important feature for the progression of hepatocellular carcinoma (HCC). Long noncoding RNA nuclear receptor subfamily 2 group F member 1 antisense RNA 1 (NR2F1-AS1) is dysregulated in HCC. However, the role and mechanism of N2RF1-AS1 in hypoxia-induced glycolysis and migration remain unclear. Materials and Methods Tumor ti...
Wang, Jia Wang, Junyu Wei, Bing
Published in
Therapeutics and Clinical Risk Management
Background Studies have shown that a variety of blood inflammatory markers can be used to assess the criticality of patients with sepsis. In this study, the blood inflammatory factors related to the sepsis survival group and the death group were compared and analyzed, which can be used by clinicians to adjust sepsis patient treatment. Methods This ...
Light, Jeremy G Su, Jennifer J Feldman, Steven R
Published in
Clinical, Cosmetic and Investigational Dermatology
Psoriasis is a chronic immune-mediated disease involving complex interaction of T cells and keratinocytes. The comprehensive pathogenesis of psoriasis is not fully understood but the IL-23/Th17 axis is a central pathway in driving disease development. Guselkumab is the first treatment of moderate-to-severe psoriasis that specifically targets the p1...
Alqanatish, Jubran Alsowailmi, Banan Alfarhan, Haneen Alhamzah, Albandari Alharbi, Talal
Published in
Open Access Rheumatology : Research and Reviews
Hereditary hemochromatosis (HH) is an inherited iron overload. The most common form of HH is type 1 hereditary hemochromatosis (HFE-related), which is associated with mutation of the HFE gene located on chromosome 6 and inherited in an autosomal recessive pattern. Type 2 hereditary hemochromatosis or juvenile hemochromatosis is less frequent autoso...
Homann, Katharina Bertsche, Thilo Schiek, Susanne
Published in
Journal of Multidisciplinary Healthcare
Purpose Older patients are still not sufficiently integrated into multidisciplinary care concepts including geriatric and palliative care. They do, however, regularly visit pharmacies to fill prescriptions or to buy self-medication. Thus, they have frequent contact with pharmacy technicians (PTs), who are widely involved in counselling in Germany. ...
Yang, Chengwei Kang, Fang Meng, Wenjun Dong, Meirong Huang, Xiang Wang, Sheng Zuo, Zhiyi Li, Juan
Published in
Clinical Interventions in Aging
Background An increasing number of patients with Parkinson’s disease (PD) will have surgery under general anesthesia. A previous study demonstrated that propofol requirement for inducing unconsciousness in PD patients was lower than that in non-PD (NPD) patients. However, the requirement of inhaled anesthetics in PD patients has not been clarified....
Liu, Xinxin Shi, Dandan Guo, Lu Zhou, Xiaoying Shang, Mengmeng Sun, Xiao Meng, Dong Zhao, Yading Li, Jie
Published in
International Journal of Nanomedicine
Purpose To synthesize echogenic chitosan/perfluorohexane nanodroplets (CNDs) for DKK-2 gene delivering in a spatiotemporally controlled manner in vitro. Methods The characteristics, contrast-enhanced ultrasound imaging, DNA binding and DNase protection capacity, DKK-2 gene transfection and effects on LNCaP cells of these CNDs were investigated. Resu...
Vingopoulos, Filippos Koulouri, Ismini Miller, John B Vavvas, Demetrios G
Published in
Clinical Ophthalmology (Auckland, N.Z.)
Purpose To investigate the nature of anatomical and functional recovery kinetics after epiretinal membrane (ERM) removal. Methods The records of 42 patients (45 eyes) with idiopathic ERM treated with pars plana vitrectomy and surgical peeling of the ERM performed by a single surgeon at Massachusetts Eye and Ear between 2012 and 2017 were retrospect...
Świątoniowska-Lonc, Natalia Polański, Jacek Tański, Wojciech Jankowska-Polańska, Beata
Published in
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Background Elderly patients with diabetes have a significantly increased prevalence of mild cognitive impairment compared with people of similar age without diabetes. Tasks related to diabetes self-management involve multiple cognitive skills and processes, such as memory, attention, planning, and calculating. Impaired cognitive function can threat...
Dalky, Heyam F Ghader, Nariman Al Kuwari, Muna Alnajar, Malek Ismaile, Samantha Almalik, Mona Shudifat, Raed Sanad, Sarah Al-Nsair, Nezam Al Matrooshi, Fatima
...
Published in
Journal of Multidisciplinary Healthcare
Background Since COVID-19 surfaced in December 2019, health-care organizations across the globe have struggled to maintain the safety and well-being of health-care professionals (HCPs). Purpose This study investigates the HCPs’ general understanding of the health risks of COVID-19 and to what extent they are equipped with the knowledge to protect t...
