Tekel, Masho Tigabe Bekalu, Abaynesh Fentahun Sema, Faisel Dula
Published in
Advances in Medical Education and Practice
Background The adequate knowledge, attitude, and practice (KAP) of pharmacovigilance and ADRs reporting is crucial for health care students. Objective This study aimed at assessing the KAP of final-year medical, pharmacy, and nursing (MPN) students towards pharmacovigilance and ADRs reporting at the University of Gondar, College of Medicine and Hea...
Wang, Meng-Jie Zhao, Yu-Hang Fan, Chen Wang, Ying-Jie Wang, Xin-Qi Qiu, Xiang-Jun Shen, Rui-Le
Published in
Drug Design, Development and Therapy
Background Upadacitinib, a novel selective Janus kinase 1 (JAK1) inhibitor, has been recently approved by the US FDA for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA). An ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the quantitative analysis of upadacitinib i...
Chiruvella, Varsha Guddati, Achuta Kumar
Published in
International Journal of General Medicine
Background Squamous cell carcinoma of the nasopharynx, oropharynx and hypopharynx constitutes a majority of head neck malignancies. The incidence-based mortality across different races has been noted to be divergent. This study analyzes the trend in incidence-based mortality from the years 2000 to 2017 amongst both the genders in Caucasian/White an...
Kirsten, Natalia Mohr, Nicole Augustin, Matthias
Published in
Clinical, Cosmetic and Investigational Dermatology
Purpose Although acne vulgaris (AV) is a common disease and can persist into adulthood, there are few large-scale epidemiological studies on the prevalence of acne vulgaris in adults. The aim of our study was to characterise the epidemiology and comorbidity of acne vulgaris in working adults in Germany. Patients and Methods Within the framework of ...
Han, Changhui Liu, Yingjuan Fan, Huanfang Li, Dehui Guo, Na
Published in
Clinical Epidemiology
Cancer pain is a common problem in clinical cancer therapy. Opioid analgesia is one of the most effective drugs for pain relief with satisfying performance besides the side effect of opioid-induced constipation (OIC). Acupuncture, as a Chinese traditional non-invasive intervention, has been applied to clinical cancer pain management and functional ...
Chen, Xin Yu, Zhicheng Wang, Jianhua Cui, Wenjing Cui, Can Wang, Yajie Liu, Yongkang Zhou, Hao Wang, Cheng Wang, Zhongqiu
...
Published in
Cancer Management and Research
Purpose The purpose of this study was to analyze the prevalence of and risk factors for incidental pancreatic cystic lesions (PCLs) in the Chinese general population. Furthermore, the association between baseline imaging findings and PCL progression was also investigated. Patients and Methods A total of 9826 individuals who underwent computed tomog...
Wang, Xiaoyu Li, Guangbing Guo, Changfa Zhang, Jiayao Kong, Junjie He, Jingyi Li, Feiyu Liu, Yong Yang, Yang Lu, Ziwen
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Published in
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Background The AMP-activated protein kinase alpha (AMPKα) pathway has widely been considered a key factor in energy metabolism. Ethyl 2-[2,3,4-trimethoxy-6-(1-octanoyl)phenyl] acetate (TMPA) is a novel AMPK agonist, which influences the stability of Nuclear Receptor Subfamily 4, Group A, Member 1 (Nur77)-serine-threonine kinase 11 (LKB1) in the nuc...
Zhu, Yuansong Shen, Jian Xue, Yuzhou Xiang, Zhenxian Jiang, Yi Zhou, Wei Luo, Suxin
Published in
International Journal of General Medicine
Objective Thyroid hormones are closely related to the cardiovascular system. Our study aimed to explore the impact of admission thyroid-stimulating hormone (TSH) levels on long-term outcomes in patients with acute ST segment elevation myocardial infarction (STEMI) by detailed stratifications of TSH. Methods Consecutive STEMI patients admitted to ou...
Azimi, Mahmoodullah Dehzad, Wazhma Masoom Atiq, Mohammad Asif Bahain, Barin Asady, Abdullah
Published in
Infection and Drug Resistance
Purpose To evaluate the occurrence, extent, and severity of adverse reactions associated with the vaccine of COVID-19 (ChAdOx1 nCoV-19 vaccine or AstraZeneca) among Kabul University of Medical Sciences staff. Patients and Methods A retrospective observational, interview-based study was conducted from 4 to 20 April, 2021, to evaluate the adverse rea...
Pai, Aswin Anand Mohan, Ajith Benjamin, Esther Sathya Bama Illangeswaran, Raveen Stephen Stallon Xavier Raj, Infencia Janet, Nancy Beryl Arunachalam, Arun Kumar Kavitha, M L Kulkarni, Uday Devasia, Anup J
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Published in
Pharmacogenomics and Personalized Medicine
Purpose Severe myelosuppression in patients with acute lymphoblastic leukemia (ALL) undergoing 6-MP-based maintenance therapy is attributed to TPMT gene polymorphisms, which is rare in Asian populations. This study aims to evaluate the role of selected polymorphisms in NUDT15, ITPA , and MRP4 genes in addition to TPMT in predicting 6-MP intolerance...
