Windhaber, Christina Heckl, Anna Csukovich, Georg Pratscher, Barbara Burgener, Iwan Anton Biermann, Nora Dengler, Franziska
Published in
Veterinary Research
Epithelial damage due to gastrointestinal disorders frequently causes severe disease in horses. To study the underlying pathophysiological processes, we aimed to establish equine jejunum and colon enteroids (eqJE, eqCE) mimicking the in vivo epithelium. Therefore, enteroids were cultivated in four different media for differentiation and subsequentl...
Yi, Heyou Ye, Ruirui Xie, Ermin Lu, Lechen Wang, Qiumei Wang, Shaojun Sun, Yankuo Tian, Tao Qiu, Yingwu Wu, Qianwen
...
Published in
Veterinary Research
Porcine reproductive and respiratory syndrome virus (PRRSV) is a viral pathogen with substantial economic implications for the global swine industry. The existing vaccination strategies and antiviral drugs offer limited protection. Replication of the viral RNA genome encompasses a complex series of steps, wherein a replication complex is assembled ...
Yang, Xiwang Liu, Rui Du, Yunsha Mei, Caiqiu Zhang, Guangneng Wang, Chen Yang, Yijun Xu, Zhiwen Li, Wenting Liu, Xiao
...
Published in
Veterinary Research
Senecavirus A (SVA) causes outbreaks of vesicular disease in pigs, which imposes a considerable economic burden on the pork industry. As current SVA prevention measures are ineffective, new strategies for controlling SVA are urgently needed. Circular (circ)RNA is a newly characterized class of widely expressed, endogenous regulatory RNAs, which hav...
Zhao, Guangfu Tang, Yunhan Liu, Xiongli Li, Pan Zhang, Tianci Li, Nengzhang He, Fang Peng, Yuanyi
Published in
Veterinary Research
Pasteurella multocida is an opportunistic zoonotic pathogen that primarily causes fatal respiratory diseases, such as pneumonia and respiratory syndromes. However, the precise mechanistic understanding of how P. multocida disrupts the epithelial barrier in mammalian lung remains largely unknown. In this study, using unbiased RNA-seq analysis, we fo...
Li, Dezhi Liang, Wei Huang, Zhiqiang Ma, Wenwen Liu, Qing
Published in
Veterinary Research
In the last decade, prophages that possess the ability of lysogenic transformation have become increasingly significant. Their transfer and subsequent activity in the host have a significant impact on the evolution of bacteria. Here, we investigate the role of prophage phi456 with high spontaneous induction in the bacterial genome of Avian pathogen...
Somenzi, Elisa Partel, Erika Barbato, Mario Chero Osorio, Ana María Colli, Licia Franceschi, Niccolò Mantovani, Roberto Pilla, Fabio Komjanc, Matteo Achilli, Alessandro
...
Published in
Genetics, Selection, Evolution : GSE
Background Rendena is a dual-purpose cattle breed, which is primarily found in the Italian Alps and the eastern areas of the Po valley, and recognized for its longevity, fertility, disease resistance and adaptability to steep Alpine pastures. It is categorized as 'vulnerable to extinction' with only 6057 registered animals in 2022, yet no comprehen...
Chuang, Edward Y. S. Wellmann, Robin Meijboom, Franck L. B. Tetens, Jens Bennewitz, Jörn
Published in
Genetics, Selection, Evolution : GSE
Background In spite of being controversial and raising ethical concerns, the application of gene editing is more likely to be accepted when it contributes to improving animal welfare. One of the animal welfare and ethical issues in chicken breeding is chick culling, the killing of the male layer chicks after hatching due to the poor fattening perfo...
Sun, Zhuo An, Qi Li, Yuepeng Gao, Xiang Wang, Hongbin
Published in
Veterinary Research
A novel variant of rabbit haemorrhagic disease virus, designated RHDV2/b/GI.2, was first discovered in France in 2010. Subsequently, RHDV2 rapidly spread to Africa, North America, Australia, and Asia. RHDV2 outbreaks have resulted in significant economic losses in the global rabbit industry and disrupted the balance of natural ecosystems. Our study...
Zhang, Zhou Ai, Huashui Huang, Lusheng
Published in
Genetics, Selection, Evolution : GSE
Anas , is a genus of dabbling ducks and encompasses a considerable number of species, among which some are the progenitors of domestic ducks. However, the taxonomic position of the Anas genus remains uncertain because several of its species, initially categorized as Anas based on morphological characteristics, were subsequently reclassified and gro...
Cochet, Marielle Piumi, François Gorna, Kamila Berry, Noémie Gonzalez, Gaëlle Danckaert, Anne Aulner, Nathalie Blanchet, Odile Zientara, Stéphan Donadeu, Francesc Xavier
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Published in
Veterinary Research
Outbreaks of West Nile virus (WNV) occur periodically, affecting both human and equine populations. There are no vaccines for humans, and those commercialised for horses do not have sufficient coverage. Specific antiviral treatments do not exist. Many drug discovery studies have been conducted, but since rodent or primate cell lines are normally us...
