Goeman F Manni I Artuso S Ramachran B Toietta G Bossi G Cencioni C Germoni S Straino S Capogrossi MC
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Published in
Molecular Biology of the Cell
In vivo imaging involving the use of genetically engineered animals is an innovative powerful tool for the noninvasive assessment of the molecular and cellular events that are often targets of therapy. On the basis of the knowledge that the activity of the nuclear factor-Y (NF-Y) transcription factor is restricted in vitro to proliferating cells, w...
Dui, Wen Wei, Bin He, Feng Lu, Wei Li, Changqing Liang, Xuehong Ma, Jun Jiao, Renjie
Published in
Molecular Biology of the Cell
Cell cycle progression is controlled by a complex regulatory network consisting of interacting positive and negative factors. In humans, the positive regulator Skp2, an F-box protein, has been a subject of intense investigation in part because of its oncogenic activity. By contrast, the molecular and developmental functions of its Drosophila homolo...
F. Goeman I. Manni S. Artuso B. Ramachandran G. Toietta G. Bossi G. Rando C. Cencioni S. Germoni S. Straino
...
Published in
Molecular Biology of the Cell
Published in
Molecular Biology of the Cell
Recent studies have underscored a role for the epicardium as a source of multipotent cells. Here, we investigate the myogenic potential of adult human epicardium-derived cells (EPDCs) and analyze their ability to undergo skeletal myogenesis when cultured with differentiating primary myoblasts. Results are compared to those obtained with mesenchymal...
A. Gentile Gabriele Toietta V. Pazzano V. D. Tsiopoulos A. F. Giglio F. Crea G. Pompilio M. C. Capogrossi G. Di Rocco
Published in
Molecular Biology of the Cell
Recent studies have underscored a role for the epicardium as a source of multipotent cells. Here, we investigate the myogenic potential of adult human epicardium-derived cells (EPDCs) and analyze their ability to undergo skeletal myogenesis when cultured with differentiating primary myoblasts. Results are compared to those obtained with mesenchymal...
Cernotta, N. Clocchiatti, Andrea Cristina Florean Brancolini, Claudio
Published in
Molecular Biology of the Cell
HDAC4 (histone deacetylase 4) belongs to class IIa of histone deacetylases, which groups important regulators of gene expression, controlling pleiotropic cellular functions. Here we show that, in addition to the well-defined nuclear/cytoplasmic shuttling, HDAC4 activity is modulated by the ubiquitin–proteasome system. Serum starvation elicits the p...
Chiu, Tim Ting Patel, Nish Shaw, Alisa E Bamburg, James R Klip, Amira
Published in
Molecular Biology of the Cell
GLUT4 vesicles are actively recruited to the muscle cell surface upon insulin stimulation. Key to this process is Rac-dependent reorganization of filamentous actin beneath the plasma membrane, but the underlying molecular mechanisms have yet to be elucidated. Using L6 rat skeletal myoblasts stably expressing myc-tagged GLUT4, we found that Arp2/3, ...
Mukhopadhyay, Somshuvra Bachert, Collin Smith, Donald R Linstedt, Adam D
Published in
Molecular biology of the cell
Manganese is an essential element that is also neurotoxic at elevated exposure. However, mechanisms regulating Mn homeostasis in mammalian cells are largely unknown. Because increases in cytosolic Mn induce rapid changes in the localization of proteins involved in regulating intracellular Mn concentrations in yeast, we were intrigued to discover th...
V Jantsch L Tang P Pasierbek A Penkner S Nayak A Baudrimont Tim Schedl A Gartner J. Loidl
Published in
Molecular Biology of the Cell
NCBI GEO standards and services for microarray data Ron Edgar and Tanya Barrett National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), National Institutes of Health (NIH), 45 Center Drive, Bethesda, MD 20892-6511, Email: [email protected] The Minimum Information About a Microarray Experiment (MIAME) guidelines ...
