Peace, Shane T. Johnson, Benjamin C. Werth, Jesse C. Li, Guoshi Kaiser, Martin E. Fukunaga, Izumi Schaefer, Andreas T. Molnar, Alyosha C. Cleland, Thomas A.
Published in
Journal of Neurophysiology
Spike timing-based representations of sensory information depend on embedded dynamical frameworks within neuronal networks that establish the rules of local computation and interareal communication. Here, we investigated the dynamical properties of olfactory bulb circuitry in mice of both sexes using microelectrode array recordings from slice and i...
Alastruey, Jordi Charlton, Peter H. Bikia, Vasiliki Paliakaitė, Birute Hametner, Bernhard Bruno, Rosa Maria Mulder, Marijn P. Vennin, Samuel Piskin, Senol Khir, Ashraf W.
...
Arterial pulse waves (PWs) such as blood pressure and photoplethysmogram signals contain a wealth of information on the cardiovascular (CV) system that can be exploited to assess vascular age and identify individuals at elevated CV risk. We review the possibilities, limitations, complementarity, and differences of reduced-order, biophysical models ...
Balistrieri, Angela Makino, Ayako Yuan, Jason X-J
Published in
Physiological reviews
The pulmonary circulation is a low-resistance, low-pressure, and high-compliance system that allows the lungs to receive the entire cardiac output. Pulmonary arterial pressure is a function of cardiac output and pulmonary vascular resistance, and pulmonary vascular resistance is inversely proportional to the fourth power of the intraluminal radius ...
Vaill, Michael Kawanishi, Kunio Varki, Nissi Gagneux, Pascal Varki, Ajit
Published in
Physiological reviews
Anthropogeny is a classic term encompassing transdisciplinary investigations of the origins of the human species. Comparative anthropogeny is a systematic comparison of humans and other living nonhuman hominids (so-called "great apes"), aiming to identify distinctly human features in health and disease, with the overall goal of explaining human ori...
Crowther, Gregory J Knight, Thomas A
Published in
Advances in physiology education
The past ∼15 years have seen increasing interest in defining disciplinary core concepts. Within the field of physiology, Michael, McFarland, Modell, and colleagues have published studies that defined physiology core concepts and have elaborated many of these as detailed conceptual frameworks. With such helpful definitions now in place, attention is...
SenthilKumar, Gopika Verhagen, Nathaniel B Sheriff, Salma A Yang, Xin Figueroa Castro, Carlos E Szabo, Aniko Taylor, Brad W Wainaina, Njeri Lauer, Kathryn Gould, Jon C
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Published in
American journal of physiology. Heart and circulatory physiology
As the coronavirus disease 2019 (COVID-19) pandemic progresses to an endemic phase, a greater number of patients with a history of COVID-19 will undergo surgery. Major adverse cardiovascular and cerebrovascular events (MACE) are the primary contributors to postoperative morbidity and mortality; however, studies assessing the relationship between a ...
Wenner, Megan M Welti, Laura M Dow, Caitlin A Greiner, Jared J Stauffer, Brian L DeSouza, Christopher A
Published in
American journal of physiology. Heart and circulatory physiology
Endothelin-1 (ET-1) contributes to vascular dysfunction in postmenopausal women (PMW). Although aerobic exercise is beneficial in reducing ET-1-mediated vasoconstrictor tone in men, it is unknown whether this favorable vascular effect occurs in women. We tested the hypothesis that aerobic exercise training reduces ET-1-mediated vasoconstriction in ...
Kanashiro-Takeuchi, Rosemeire M Takeuchi, Lauro M Dulce, Raul A Kazmierczak, Katarzyna Balkan, Wayne Cai, Renzhi Sha, Wei Schally, Andrew V Hare, Joshua M
Published in
American journal of physiology. Heart and circulatory physiology
Heart failure (HF) with preserved ejection fraction (HFpEF) represents a major unmet medical need owing to its diverse pathophysiology and lack of effective therapies. Potent synthetic, agonists (MR-356 and MR-409) of growth hormone-releasing hormone (GHRH) improve the phenotype of models of HF with reduced ejection fraction (HFrEF) and in cardiore...
Khan, Muhammad S Smego, Douglas Ishidoya, Yuki Hirahara, Annie M Offei, Emmanuel Ruiz Castillo, Martha S Gharbia, Omar Li, Hui Palatinus, Joseph A Krueger, Lauren
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Published in
American journal of physiology. Heart and circulatory physiology
Preclinical large animal models of chronic heart failure (HF) are crucial to both understanding pathological remodeling and translating fundamental discoveries into novel therapeutics for HF. Canine models of ischemic cardiomyopathy are historically limited by either high early mortality or failure to develop chronic heart failure. Twenty-nine heal...
Mao, Shuangfa Guo, Linghong Li, Pengjie Shen, Kui Jiang, Mingxia Liu, Yin
Published in
Advances in physiology education
COVID-19 struck the world suddenly and unexpectedly. Since traditional education requires face-to-face communication, to avoid further spreading of the virus a majority part of that education has moved online. Our study attempts to compare the differences between online medical education with a unique course design and traditional face-to-face educ...
