Herrmann, Markus Keppel, Martin H. Zelzer, Sieglinde Alonso, Nerea Cavalier, Etienne Kleber, Marcus Enko, Dietmar Scharnagl, Hubert Pilz, Stefan März, Winfried
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Published in
Clinical Chemistry and Laboratory Medicine (CCLM)
Objectives The role of vitamin D deficiency in cardiovascular disease (CVD) is controversial. Inherent biological and analytical limitations compromise the specificity of widely used 25-hydroxyvitamin D [25(OH)D] cut-offs. Simultaneous determination of 25(OH)D and 24,25-dihydroxyvitamin D [24,25(OH)2D] permits a functional assessment of vitamin D m...
a. papadopoulou, sofia neonilli anastasiou, elena a. adamantidi, theodora ofrydopoulou, anna letsiou, sophia tsoupras, alexandros
Vitamin D, also called the “sunshine” vitamin, has gained great attention recently due to the observed high percentage of the worldwide population being deficient in this essential bioactive vitamin. Primarily, vitamin D was known for its important role in bone health. Nevertheless, recent research has shown its importance for the brain, heart, mus...
michalak, filip dominiak, marzena kiryk, jan popecki, paweł kubicki, dominik matys, jacek grzech-leśniak, kinga
Background: Advancements in pharmacology have led to the introduction of novel antiresorptive and antiangiogenic drugs, which are associated with the side effect of medication-related osteonecrosis of the jaw (MRONJ). The aim of this study was to evaluate the impact of different blood levels of vitamin D on the course of treatment, as well as the r...
bösch, elana sophie spörri, jörg scherr, johannes
Background/Objectives: In recent years, there has been a growing interest in precision nutrition and its potential for disease prevention. Differences in individual responses to diet, especially among populations of different ancestry, have underlined the importance of understanding the effects of genetic variations on nutrient intake (nutrigenomic...
licata, anna seidita, aurelio como, silvia de carlo, gabriele cammilleri, marcella bonica, roberta soresi, maurizio veronese, nicola chianetta, roberta citarrella, roberto
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During the COVID-19 pandemic, several observational studies proved a certain efficacy of nutraceuticals, herbal products, and other dietary supplements as adjuvant therapies used alongside antiviral drugs. Although their use has not been widespread in Italy, according to preliminary evidence, many supplements with demonstrated immunomodulatory effe...
diaz-ruiz, raquel poca, maria roman, eva panadero-gomez, rocio cuyàs, berta bañares, irene morales, angela puerto, marta lopez-esteban, rocio blazquez, elena
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Background/Objectives: Decompensated cirrhosis is characterized by systemic inflammation and innate and adaptive immune dysfunction. Hepatic encephalopathy (HE) is a prevalent and debilitating condition characterized by cognitive disturbances in which ammonia and inflammation play a synergistic pathogenic role. Extraskeletal functions of vitamin D ...
saija, caterina bertuccio, maria paola scoglio, alberto macaione, vincenzo cacciola, francesco micalizzi, giuseppe caccamo, daniela muscoli, carolina currò, monica
Background/Objectives: Several studies suggest gut microbiota metabolites as important immuno-modulators in inflammatory pain. We aimed to investigate the relationship between vitamin D status and gut dysbiosis markers in fibromyalgia (FM)-associated chronic inflammation. Methods: Blood samples were collected from sixty-eight female FM patients (49...
Chu, Han Deng, Qi-Fei Fang, Yuan
Published in
Frontiers in Pediatrics
Introduction Cryptorchidism can damage cells in the cryptorchid testes due to elevated local temperatures, potentially impacting the fertility of the child in adulthood. Research indicates that vitamin D enhances sperm quality in adult males. This study aimed to explore whether vitamin D inhibits NLRP3 activation, thus helping to mitigate heat stre...
Huang, Limi Song, Zhiwei Lu, Chaosheng Wang, Shenwen Guo, Changsheng Lai, Xin-He Zhao, Zhenfeng
Published in
Frontiers in Nutrition
Current evidence is inconsistent on whether vitamin D supplementation can prevent COVID-19 infection or improve its clinical outcomes. To better understand and look into the issue, we went through the background knowledge of COVID-19 and vitamin D, searched in Pubmed [by using key words in the title containing “randomized clinical trial”, “COVID-19...
Almansour, Salman Alsalamah, Abdullrahman Almutlaq, Mohammad Sheikh, Ahmed Hamdan, Hamdan Z. Al-Nafeesah, Abdullah AlEed, Ashwaq Adam, Ishag Al-Wutayd, Osama
Published in
Frontiers in Pediatrics
Background The association between 25-hydroxy-vitamin D [25(OH)D] levels and glycemic control in pediatric patients with type 1 diabetes mellitus (T1DM) is unclear. In this study, we aimed to investigate the association between 25(OH)D levels and glycemic control in Saudi pediatric patients' with T1DM in a region that is sunny year-round.Materials ...