Accelerated and intensified manufacturing of an adenovirus-vectored vaccine to enable rapid outbreak response.
...Published in Biotechnology and bioengineering
The Coalition for Epidemic Preparedness Innovations' "100-day moonshot" aspires to launch a new vaccine within 100 days of pathogen identification, followed by large-scale vaccine availability within the "second hundred days." Here, we describe work to optimize adenoviral vector manufacturing for rapid response, by minimizing time to clinical trial...