Patberg, Elizabeth T. Adams, Tracy Rekawek, Patricia Vahanian, Sevan A. Akerman, Meredith Hernandez, Andrea Rapkiewicz, Amy V. Ragolia, Louis Sicuranza, Genevieve Chavez, Martin R.
...
Published in
American Journal of Obstetrics and Gynecology
Background There is a paucity of data describing the effects of coronavirus disease 2019 on placental pathology, especially in asymptomatic patients. Although the pathophysiology of coronavirus disease 2019 is not completely understood, there is emerging evidence that it causes a severe systemic inflammatory response and results in a hypercoagulabl...
Romero, Roberto Kim, Yeon Mee Pacora, Percy Kim, Chong Jai Benshalom-Tirosh, Neta Jaiman, Sunil Bhatti, Gaurav Kim, Jung-Sun Qureshi, Faisal Jacques, Suzanne M.
...
Published in
Journal of Perinatal Medicine
Objective To determine the frequency and type of histopathologic lesions in placentas delivered by women with a normal pregnancy outcome. Methods This retrospective cohort study included placental samples from 944 women with a singleton gestation who delivered at term without obstetrical complications. Placental lesions were classified into the fol...
Derricott, Hayley Heazell, Alexander E P Greenwood, Susan L Jones, Rebecca L
Published in
American journal of reproductive immunology (New York, N.Y. : 1989)
Placental dysfunction is present over 50% of cases of stillbirth and fetal growth restriction (FGR). Villitis of unknown etiology (VUE), an inflammatory condition of the placenta characterized by maternal T cell infiltrates in the villous stroma and dysregulation of inflammatory cytokines, is more frequent in FGR and stillbirth. A novel in vitro mo...
Kovo, Michal Ganer Herman, Hadas Gold, Eran Bar, Jacob Schreiber, Letizia
Published in
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
VUE is associated with lower birth weights, SGA and lower placental weight. Both VUE and maternal malperfusion lesions are risk factors for the development of SGA.
Benzon, Sandra Zekić Tomaš, Sandra Benzon, Zdeslav Vulić, Marko Kuzmić Prusac, Ivana
Published in
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
The higher immunohistochemical CD4 positive T lymphocyte count and CD4 positive/CD8 positive ratio in placentae with VUE complicated with PE could point to their role in ethiopathogenesis of PE.
Benzon, Sandra Zekić Tomaš, Sandra Benzon, Zdeslav Vulić, Marko Kuzmić Prusac, Ivana
Published in
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
The higher immunohistochemical CD4 positive T lymphocyte count and CD4 positive/CD8 positive ratio in placentae with VUE complicated with PE could point to their role in ethiopathogenesis of PE.
Redline, Raymond W. Ariel, Ilana Baergen, Rebecca N. deSa, Derek J. Kraus, Frederick T. Roberts, Drucilla J. Sander, C. Maureen
Published in
Pediatric and Developmental Pathology
The purpose of this study was to assemble and test the reliability of a complete set of the placental reaction patterns seen with chronic fetal vascular obstruction in the hope that this might provide a standardized diagnostic framework useful for practicing pathologists. Study cases (14 with fetal vascular obstructive lesions, 6 controls) were rev...
