Global Review of the Age Distribution of Rotavirus Disease in Children Aged
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We sought datasets with granular age distributions of rotavirus-positive disease presentations among children
HPV-Impfung: Ab dem 9. Lebensjahr bei jedem Praxisbesuch ansprechen!
Published in MMW - Fortschritte der Medizin
Mit der Ausweitung der HPV-Impfempfehlung auf Jungen im Alter von 9 bis 17 Jahren soll die Krankheitslast aller HPV-assoziierten Tumoren reduziert werden. Was Sie tun können, damit sich die bisher noch geringen Impfquoten verbessern, erfahren Sie im nachfolgenden Beitrag.
Der neue Zoster-Totimpfstoff: Wen, wann, wie impfen?
Published in MMW - Fortschritte der Medizin
Seit Dezember 2018 empfiehlt die STIKO den adjuvantierten Zoster-Totimpfstoff als Standard- und Indikationsimpfung, und seit Mai 2019 sind die gesetzlichen Kassen zur Kostenübernahme verpflichtet. Praxisrelevante Fragen und Antworten zum neuen Impfstoff finden Sie hier.
Impfen bei Immunschwäche: Das ist zu beachten
Published in MMW - Fortschritte der Medizin
Impfen ist insbesondere bei immundefizienten Patienten eine wichtige Schutzmaßnahme. Welche Impfungen sind unproblematisch, welche müssen gut abgewogen werden? Welches Vorgehen ist vor geplanter Immunsuppression empfehlenswert?
Neutralization of rhesus cytomegalovirus IL-10 reduces horizontal transmission and alters long-term immunity.
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Human cytomegalovirus (HCMV) causes severe disease in infants and immunocompromised people. There is no approved HCMV vaccine, and vaccine development strategies are complicated by evidence of both persistent infection and reinfection of people with prior immunity. The greatest emphasis has been placed on reducing transmission to seronegative pregn...
Evaluation of a canine transmissible venereal tumour cell line with tumour immunity capacity but without tumorigenic pro...
Published in Journal of Veterinary Research
Introduction Canine transmissible venereal tumour (CTVT) is a sexually transmitted tumour affecting dogs worldwide, imposing a financial burden on dog owners. A stable culture cell line in continuous passages for >18 months has only been achieved once. The present study investigated a stable CTVT cell line isolated from a bitch and its potential as...
Protein and Peptide Biomaterials for Engineered Subunit Vaccines and Immunotherapeutic Applications
Although vaccines have been the primary defense against widespread infectious disease for decades, there is a critical need for improvement to combat complex and variable diseases. More control and specificity over the immune response can be achieved by using only subunit components in vaccines. However, these often lack sufficient immunogenicity t...
Kaposi Sarcoma-associated Herpesvirus Glycoprotein H is Indispensable for Infection of Epithelial, Endothelial, and Fibr...
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Kaposi sarcoma-associated herpesvirus (KSHV) is an emerging pathogen and is the causative infectious agent of Kaposi sarcoma and two malignancies of B cell origin. To date, there is no licensed KSHV vaccine. Development of an effective vaccine against KSHV continues to be limited by a poor understanding of how the virus initiates acute primary infe...
In vitro evaluation of chitosan-DNA plasmid complex encoding Jembrana disease virus Env-TM protein as a vaccine candidat...
Published in Journal of Veterinary Research
Introduction The development of Jembrana disease vaccine is an important effort to prevent losses in the Bali cattle industry in Indonesia. This study aims to prepare a Jembrana DNA vaccine encoding the transmembrane portion of the envelope protein in pEGFP-C1 and test the success of its delivery in culture cells using a chitosan-DNA complex. Mater...
A Method for Enhancing the Efficacy of Vaccination and Reducing the Frequency of Infectious Abortion in Herd Horse Breed...
Published in Russian Agricultural Sciences
AbstractThe probiotic formulation Sakhabactisubtil based on the strains of Bacillus subtilis with zeolite can increase the immunogenicity of inactivated vaccines used to prevent rhinopneumonitis and salmonellosis abortions in herd horse breeding. By the end of the study in March, pregnant mares of the experimental group had a higher level of normal...
