Published in Microbiology Spectrum
Uropathogenic Escherichia coli (UPEC) is one of the most common causes of urinary tract infections. Here, we report for the first time the whole-genome sequencing (WGS) and analysis of four extended-spectrum β-lactamase (ESBL), UPEC sequence type (ST) 127 isolates that were recovered from patients in five hospitals in Armenia from January to August...
Published in Bulletin of experimental biology and medicine
The biofilm formation by uropathogenic E. coli (UPEC) allows bacteria to avoid the influence of the host immune system that determines the pathogenesis of persistent urinary tract infections. The purpose of this work was to evaluate the mutual influence of neutrophils and biofilms formed by UPEC with different set of virulence-associated genes (VAG...
Published in Microbial drug resistance (Larchmont, N.Y.)
Introduction: Uropathogenic Escherichia coli (UPECs) are a significant cause of urinary tract infections (UTIs). In Kenya, UTIs are typically treated with β-lactam antibiotics without antibiotic susceptibility testing, which could accelerate antibiotic resistance among UPEC strains. Aim: This study determined the occurrence of UPEC producing extend...
Published in Klinicheskaia laboratornaia diagnostika
The aim of the study was to evaluate the genetic affinity of uropathogenic E. coli cultures (UPEC) and to identify the major types of extended spectrum beta-lactamases (ESBL) found among nosocomial isolates. A molecular typing of UPEC (n=93) isolated from patients with urinary tract infections (UTI) who were hospitalised in nine medical facilities ...
Published in Frontiers in Microbiology
Background Inflammatory response during urinary tract infection (UTI) is mediated by innate immune defense. Nod like receptors (NLRs) have been proposed to work simultaneously beside TLR pathways to mediate pro-inflammatory response and maintain tissue homeostasis. Some in vitro reports have showed the involvement of NLRP3 inflammasome during uropa...
Published in Urologiia (Moscow, Russia : 1999)
The etiological structure of urinary tract infections (UTI) is determined by the leading role of uropathogenic Escherichia coli (UPEC). The aim of the work is to study the biological properties and phylogenetic diversity of E. coli strains isolated from UTI in outpatient and inpatient patients. s and materials. 198 clinical UPEC strains were studie...
