Ishimaru, Kei Akita, Satoshi Matsuda, Shunji Yukumi, Shungo Morimoto, Masamitsu Kikuchi, Chiya Matsui, Sayuri Tanigawa, Kazufumi Kuwabara, Jun Matsumoto, Hironori
...
Published in
Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
The increasing age of patients with severe motor and intellectual disabilities (SMID) has become a serious concern. Few studies have investigated tumor treatment in this population. Tumor treatments for 12 SMID patients were examined. Blood tests and ultrasonography were useful for screening. With regard to treatment, surgery for SMID patients was ...
Dong, Ruoyu Zhang, Yixi Xiao, Haowen Zeng, Xun
Published in
Frontiers in Immunology
Adoptive cell therapy (ACT) with engineered T cells has emerged as a promising strategy for the treatment of malignant tumors. Among them, there is great interest in engineered γδ T cells for ACT. With both adaptive and innate immune characteristics, γδ T cells can be activated by γδ TCRs to recognize antigens in a MHC-independent manner, or by NK ...
Lans, Jonathan Yue, Kai-Lou C Castelein, René M Suster, David I Petur Nielsen, G Chen, Neal C Lozano-Calderon, Santiago A
Published in
Hand (New York, N.Y.)
Background: Benign soft-tissue tumors of the hand are more common than both their benign bone and malignant soft-tissue counterparts. This study evaluates the characteristics and treatment of benign soft tissue tumors in light of 1 institution's experience. Methods: Histologically confirmed benign soft-tissue tumors of the hand were retrospectively...
Kataoka, Yuko Sonoda, Kazutaka Takahashi, Jun C Ishibashi-Ueda, Hatsue Toyoda, Kazunori Yakushiji, Yusuke Kusaka, Hirofumi Koga, Masatoshi
Published in
Journal of neurointerventional surgery
The procoagulant state in cancer increases the thrombotic risk, and underlying cancer could affect treatment strategies and outcomes in patients with ischemic stroke. However, the histopathological characteristics of retrieved thrombi in patients with cancer have not been well studied. This study aimed to assess the histopathological difference bet...
Vasilevska Nikodinovska, Violeta Ivanoski, Slavcho Kostadinova-Kunovska, Slavica Samardziski, Milan
Published in
Journal of Ultrasonography
The aim of this article is to provide a short review of the literature concerning the basic principles, usefulness and limitations of ultrasound-guided biopsy of musculoskeletal soft-tissue tumors, with particular focus on core needle biopsies. Musculoskeletal soft-tissue tumors represent a rare and complex group of heterogeneous lesions. Prompt di...
Kimura, Jiro Okabayashi, Takehiro Sui, Kenta Tabuchi, Motoyasu Iwata, Jun Hata, Yasuhiro Iiyama, Tatsuo Ono, Noriaki
Small bowel metastasis from renal cell carcinoma (RCC) is rare, and its clinicopathological characteristics are unclear; thus, we revisited the concept of this tumor and reviewed its diagnostic and treatment modalities. We filtered MEDLINE searches of articles published in English between 1950 and 2019, and identified 100 patients who had undergone...
Xu, Jiangyan Zhang, Jinrong Mao, Qi-Fen Wu, Jian Wang, Yuan
Published in
Frontiers in Genetics
Tumor is one of the important factors affecting human life and health in today’s world, and scientists have studied it extensively and deeply, among which autophagy and JAK/STAT3 signaling pathway are two important research directions. The JAK/STAT3 axis is a classical intracellular signaling pathway that assumes a key role in the regulation of cel...
Liao, Haiqin Niu, Chengcheng
Published in
Frontiers in Bioengineering and Biotechnology
Many cancers have evolved various mechanisms to evade immunological surveillance, such as the inhibitory immune checkpoint of the CD47-SIRPα signaling pathway. By targeting this signaling pathway, researchers have developed diverse nanovehicles with different loaded drugs and modifications in anticancer treatment. In this review, we present a brief...
Tiwari, Dinesh Kumar Hannen, Ricarda Unger, Kristian Kohl, Sibylla Heß, Julia Lauber, Kirsten Subtil, Florentine S. B. Dikomey, Ekkehard Engenhart-Cabillic, Rita Schötz, Ulrike
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Published in
Frontiers in Oncology
Background Treatment of locally advanced HPV-negative head and neck squamous cell carcinoma (HNSCC) with photon radiation is the standard of care but shows only moderate success. Alterations in response toward DNA DSB repair, apoptosis, and senescence are underlying determinants of radioresistance in the tumor cells. Recently, senescence and the as...
Lillo, Sebastian Saleh, Maya
Published in
Frontiers in Cell and Developmental Biology
The inflammasomes are critical regulators of innate immunity, inflammation and cell death and have emerged as important regulators of cancer development and control. Inflammasomes are assembled by pattern recognition receptors (PRR) following the sensing of microbial- or danger-associated molecular patterns (MAMPs/DAMPs) and elicit inflammation thr...
