Irshad, Zehra Lund, Jenny Sillars, Anne Løvsletten, Nils Gunnar Gharanei, Seley Salt, Ian P Freeman, Dilys J Gill, Jason M R Thoresen, G Hege Rustan, Arild C
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Published in
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
The roles of DGAT1 and DGAT2 in lipid metabolism and insulin responsiveness of human skeletal muscle were studied using cryosections and myotubes prepared from muscle biopsies from control, athlete, and impaired glucose regulation (IGR) cohorts of men. The previously observed increases in intramuscular triacylglycerol (IMTG) in athletes and IGR wer...
Mikłosz, Agnieszka Łukaszuk, Bartłomiej Supruniuk, Elżbieta Grubczak, Kamil Kusaczuk, Magdalena Chabowski, Adrian
Published in
Frontiers in Molecular Biosciences
The Akt substrate of 160 kDa (AS160), also known as TBC1 domain family member 4 (TBC1D4), represents a crucial regulator of insulin-stimulated glucose uptake in skeletal muscle and adipose tissue. Recent evidence suggests that AS160/TBC1D4 may also control the cellular entry of long-chain fatty acids (LCFAs), resulting in changes to the lipid profi...
Khaddaj, Rasha Stribny, Jiri Cottier, Stéphanie Schneiter, Roger
Published in
Frontiers in Cell and Developmental Biology
Lipid droplets (LDs) serve as intracellular stores of energy-rich neutral lipids. LDs form at discrete sites in the endoplasmic reticulum (ER) and they remain closely associated with the ER during lipogenic growth and lipolytic consumption. Their hydrophobic neutral lipid core is covered by a monolayer of phospholipids, which harbors a specific set...
Guzha, Athanas Whitehead, Payton Ischebeck, Till Chapman, Kent D.
Lipid droplets, also known as oil bodies or lipid bodies, are plant organelles that compartmentalize neutral lipids as a hydrophobic matrix covered by proteins embedded in a phospholipid monolayer. Some of these proteins have been known for decades, such as oleosins, caleosins, and steroleosins, whereas a host of others have been discovered more re...
Hou, Guixue Gao, Ya Poon, Liona C Ren, Yan Zeng, Chunwei Wen, Bo Syngelaki, Argyro Lin, Liang Zi, Jin Su, Fengxia
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Published in
BJOG : an international journal of obstetrics and gynaecology
to define the lipidomic profile in plasma across pregnancy, and identify lipid biomarkers for gestational diabetes mellitus (GDM) prediction in early pregnancy. Case-control study SETTING: Tertiary referral maternity unit POPULATION OR SAMPLE: plasma samples from 100 GDM and 100 normal glucose tolerance (NGT) women, divided into a training set (GDM...
Tang, Weiwei Wang, Jiancheng Li, Wei Zhang, Chaojun Li, Ping Chen, Jun
Published in
Foods (Basel, Switzerland)
Coix seed is a kind of widespread cereal, and it is used as a folk medicine in China. The present work focuses on the analysis of changes in triacylglycerols (TAGs) content and mycotoxins of coix seed during the processing and storage period for its quality control. Using ultra-high-performance liquid chromatography coupled with quadrupole time-of-...
Knox, Sophie Hagvall, Lina Malmberg, Per O'Boyle, Niamh M.
Published in
Frontiers in Toxicology
Lipids are an important constituent of skin and are known to be modified in many skin diseases including psoriasis and atopic dermatitis. The direct effects of common metallic contact allergens on the lipid composition of skin has never been investigated, to the best of our knowledge. We describe skin lipid profiles in the stratum corneum and viabl...
arena;, paola
The growing demand in natural matrices that represent a source of dietary and nutraceutical molecules has led to an increasing interest in Cannabis sativa, considered to be a multipurpose, sustainable crop. Particularly, the considerable content in essential fatty acids (FAs) makes its derived-products useful food ingredients in the formulation of ...
Wang, Siyu Wang, Wenjun Mao, Hongmei Zhu, Mingyu Xu, Zihan Wang, Jun Zhang, Xuesong Li, Baolong Xiang, Xuesong Wang, Zhu
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Published in
Frontiers in Nutrition
The type of diet is very important for the maintenance of health and nutrition. How the sole source of carbohydrates from rice- or flour-based diet affect blood sugar has not been elucidated for a long time. In order to explore the effects of these diets, sixty SD rats were randomly divided into three groups: control group (C group, AIN-93, standar...
Zhang, Xin-Yue Li, Bing Huang, Bei-Chen Wang, Feng-Biao Zhang, Yue-Qi Zhao, Shao-Geng Li, Min Wang, Hai-Ying Yu, Xin-Jun Liu, Xiao-Yan
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Published in
Frontiers in Nutrition
Oleaginous fungi (including fungus-like protists) are attractive in lipid production due to their short growth cycle, large biomass and high yield of lipids. Some typical oleaginous fungi including Galactomyces geotrichum, Thraustochytrids, Mortierella isabellina, and Mucor circinelloides, have been well studied for the ability to accumulate fatty ...