Sreepadmanabh, M Sahu, Amit Kumar Chande, Ajit
Published in
Journal of Biosciences
An unprecedented worldwide spread of the SARS-CoV-2 has imposed severe challenges on healthcare facilities and medical infrastructure. The global research community faces urgent calls for the development of rapid diagnostic tools, effective treatment protocols, and most importantly, vaccines against the pathogen. Pooling together expertise across b...
Samidurai, Arun Das, Anindita
Published in
International Journal of Molecular Sciences
The outbreak of coronavirus disease 2019 (COVID-19), an infectious disease with severe acute respiratory syndrome, has now become a worldwide pandemic. Despite the respiratory complication, COVID-19 is also associated with significant multiple organ dysfunction, including severe cardiac impairment. Emerging evidence reveals a direct interplay betwe...
Jabbour, Elias Kantarjian, Hagop
Published in
Clinical lymphoma, myeloma & leukemia
Arteaga-Badillo, Diego A. Portillo-Reyes, Jacqueline Vargas-Mendoza, Nancy Morales-González, José A. Izquierdo-Vega, Jeannett A. Sánchez-Gutiérrez, Manuel Álvarez-González, Isela Morales-González, Ángel Madrigal-Bujaidar, Eduardo Madrigal-Santillán, Eduardo
...
Published in
Medicina
Asthma is a chronic disease whose main anatomical–functional alterations are grouped into obstruction, nonspecific bronchial hyperreactivity, inflammation and airway remodeling. Currently, the Global Initiative of Asthma 2020 (GINA 2020) suggests classifying it into intermittent cases, slightly persistent, moderately persistent and severely persist...
Imai, Tomihiro Suzuki, Shigeaki Nagane, Yuriko Uzawa, Akiyuki Murai, Hiroyuki Utsugisawa, Kimiaki
Published in
Frontiers in Neurology
Treatment with oral corticosteroids at high doses with an escalation and de-escalation schedule is effective against myasthena gravis (MG). In fact, the use of corticosteroids has led to a reduction in mortality to below 10% after the 1960s. However, long-term use of oral steroids above a certain dosage level is known to cause a number of problems....
Bansal, Ruchi Mandrekar, Pranoti Mohanty, Sujit K. Weiskirchen, Ralf
Macrophages constitute a key component of our immune system and play an important role in immune surveillance. Hepatic macrophages are a heterogeneous population of immune cells that mainly comprises of embryonically-derived resident Kupffer cells (KCs), and circulating monocyte-derived macrophages (MoMFs). They play a critical role in disease init...
Bansal, Ruchi Mandrekar, Pranoti Mohanty, Sujit K. Weiskirchen, Ralf
Published in
Frontiers in Immunology
Jamshaid, Humzah Zahid, Fatima Din, Intisar ud Zeb, Alam Choi, Han Gon Khan, Gul Majid Din, Fakhar ud
Published in
AAPS PharmSciTech
The world is facing lockdown for the first time in decades due to the novel coronavirus COVID-19 (SARS-CoV-2) pandemic. This has led to massive global economic disruption, placed additional strain on local and global public health resources and, above all, threatened human health. We conducted a review of peer-reviewed and unpublished data, written...
Nitulescu, George Mihai Paunescu, Horia Moschos, Sterghios A Petrakis, Dimitrios Nitulescu, Georgiana Ion, George Nicolae Daniel Spandidos, Demetrios A Nikolouzakis, Taxiarchis Konstantinos Drakoulis, Nikolaos Tsatsakis, Aristidis
...
Published in
International journal of molecular medicine
The major impact produced by the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) focused many researchers attention to find treatments that can suppress transmission or ameliorate the disease. Despite the very fast and large flow of scientific data on possible treatment solutions, none have yet demonstrated unequivocal clinical utility...
Liu, Ziqian Chen, Xiatian Li, Zhe Ye, Wei Ding, Hongyan Li, Peifeng Aung, Lynn Htet Htet
Published in
International Journal of Molecular Sciences
In the history of nucleic acid research, DNA has always been the main research focus. After the sketch of the human genome was completed in 2000, RNA has been started to gain more attention due to its abundancies in the cell and its essential role in cellular physiology and pathologies. Recent studies have shown that RNAs are susceptible to oxidati...