Berton, Paula Siraj, Noureen Das, Susmita de Rooy, Sergio Wuilloud, Rodolfo G Warner, Isiah M
Published in
Molecules (Basel, Switzerland)
In this study, three magnetic ionic liquids (MILs) were investigated for extraction of four estrogens, i.e., estrone (E1), estradiol (E2), estriol (E3), and ethinylestradiol (EE2), from environmental water. The cation trihexyl(tetradecyl)phosphonium ([P66614]+), selected to confer hydrophobicity to the resulting MIL, was combined with tetrachlorofe...
Signorini, Luca Ballini, Andrea Arrigoni, Roberto De Leonardis, Francesco Saini, Rajiv Cantore, Stefania De Vito, Danila Coscia, Maria Franca Dipalma, Gianna Santacroce, Luigi
...
Published in
Endocrine, metabolic & immune disorders drug targets
Dysbiosis is related to changes in composition and behaviour of intestinal microbiota, which may contribute to an age-related decline in metabolic and immune system functioning (immune-senescence). The microbiota-targeted dietary and probiotic interventions have been shown to favorably affect the host health by an enhancement of antioxidant activit...
Efron, Philip A Darden, Dijoia B Wang, Zhongkai Nacionales, Dina C Lopez, Maria-Cecilia Hawkins, Russell B Cox, Michael C Rincon, Jaimar C Ungaro, Ricardo Dirain, Marvin L
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Published in
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Historically, murine models of inflammation in biomedical research have been shown to minimally correlate with genomic expression patterns from blood leukocytes in humans. In 2019, our laboratory reported an improved surgical sepsis model of cecal ligation and puncture (CLP) that provides additional daily chronic stress (DCS), as well as adhering t...
Baracho Trindade Hill, Amanda Speri Alves, Antonio Alexandre da Silva Nunes Barreto, Rodrigo Fernandes Bressan, Fabiana Miglino, Maria Angelica Mansano Garcia, Joaquim
Published in
Journal of tissue engineering and regenerative medicine
Prudent choices of cell sources and biomaterials, as well as meticulous cultivation of the tissue microenvironment, are essential to improving outcomes of tissue engineering treatments. With the goal of providing a high-quality alternative for bone and cartilage tissue engineering, we investigated the capability of bovine placental scaffolds to sup...
Probert, Lesley Quintana, Francisco J. Bar-Or, Amit
Published in
Frontiers in Immunology
Aonuma, Kazuhiro Ferdousi, Farhana Xu, DongZhu Tominaga, Kenichi Isoda, Hiroko
Published in
Frontiers in Cell and Developmental Biology
Cardiac hypertrophy and fibrosis are major pathophysiologic disorders that lead to serious cardiovascular diseases (CVDs), such as heart failure and arrhythmia. It is well known that transforming growth factor β (TGFβ) signaling pathways play a major role in the proliferation of cardiac hypertrophy and fibrosis, which is mainly stimulated by angiot...
Saborowski, Anna Lehmann, Ulrich Vogel, Arndt
Published in
Therapeutic Advances in Medical Oncology
Patients with intrahepatic cholangiocarcinoma (iCCA) face a highly dismal prognosis, due to late stage diagnosis, the relative chemoresistance of the disease, and an overall limited portfolio of established therapeutic concepts. In recent years, a number of next generation sequencing studies have provided detailed information on the molecular lands...
Roura, Santiago Monguió-Tortajada, Marta Munizaga-Larroudé, Micaela Clos-Sansalvador, Marta Franquesa, Marcella Rosell, Anna Borràs, Francesc E.
Published in
International Journal of Molecular Sciences
Multipotent mesenchymal stromal cells (MSC) represent a promising strategy for a variety of medical applications. Although only a limited number of MSC engraft and survive after in vivo cellular infusion, MSC have shown beneficial effects on immunomodulation and tissue repair. This indicates that the contribution of MSC exists in paracrine signalin...
Funcke, Sandra Werner, Tessa R. Hein, Marc Ulmer, Bärbel M. Hansen, Arne Eschenhagen, Thomas Hirt, Marc N.
Published in
Biomolecules
Intermittent hypoxia and various pharmacological compounds protect the heart from ischemia reperfusion injury in experimental approaches, but the translation into clinical trials has largely failed. One reason may lie in species differences and the lack of suitable human in vitro models to test for ischemia/reperfusion. We aimed to develop a novel ...
Kovalev, G V Shkarupa, D D Zaytseva, A O Staroseltseva, O Y Borodulina, I V Kalinina, D S Musienko, P E
Published in
Urologiia (Moscow, Russia : 1999)
An overactive bladder (OAB) is a constellation of lower urinary tract symptoms, including urgency, increased frequency of urination during the day and/or night (nocturia), and, in some cases, urge incontinence. This syndrome can be caused by different conditions, and currently no universal pathogenetic treatment has been developed. In addition, the...
