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Behavior and possible function of Arabidopsis BES1/BZR1 homolog 2 in brassinosteroid signaling

Published in Plant Signaling & Behavior

Two key transcription factors (TFs) in brassinosteroid (BR) signaling BRASSINOSTEROID INSENSITIVE 1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE RESISTANT 1 (BZR1), belong to a small family with four BES1/BZR1 homologs (BEH1–4). To date, in contrast to the wealth of knowledge regarding BES1 and BZR1, little is known about BEH1–4. Here, we show that BEH...

In vivo enkapsulacija specifičnih fragmentov DNA v bakterijski mikrorazdelek

Bakterijski mikrorazdelki so primitivni proteinski organeli, ki jih sintetizira okrog 20 % bakterijskih vrst, katerih zaporedje genoma je določeno. Njihova glavna naloga je izboljševanje učinkovitosti posameznih metabolnih reakcij ali preprečitev akumulacije toksičnih metabolitov v citoplazmi. V osnovi jih delimo na tiste, ki sodelujejo v anabolizm...

The transcription factor Eomes promotes expression of inhibitory receptors on hepatic CD8+ T cells during HBV persistenc...

Published in The FEBS journal

Persistent infection with the hepatitis B virus (HBV) can aggravate the state of immune tolerance, inhibit the function of immune cells, and even lead to immune cell exhaustion in the liver microenvironment. The dysfunction of immune cells causes HBV to escape immune surveillance and eradication. Increasing evidence has revealed the molecular and c...

Transcription factors CncC and Maf connect the molecular network between pesticide resistance and resurgence of pest mit...

Published in Insect science

Pesticide resistance and resurgence are serious problems often occurring simultaneously in the field. In our long-term study of a fenpropathrin-resistant strain of Tetranychus cinnabaribus, enhancement of detoxification and modified fecundity mechanisms were both observed. Here we investigate the network across these two mechanisms and find a key n...

Function and regulation of transcription factors during mitosis-to-G1 transition

Published in Open Biology

During cell division, drastic cellular changes characteristic of mitosis result in the inactivation of the transcriptional machinery, and global downregulation of transcription. Sequence-specific transcription factors (TFs) have thus been considered mere bystanders, devoid of any regulatory function during mitosis. This view changed significantly i...

Regulation of the apolipoprotein M signaling pathway: a review.

Published in Journal of receptor and signal transduction research

Apolipoprotein M (apoM), an apolipoprotein predominantly associated with high-density lipoprotein (HDL), is considered a mediator of the numerous roles of HDL, including reverse cholesterol transport, anti-atherosclerotic, anti-inflammatory and anti-oxidant, and mediates pre-β-HDL formation. ApoM expression is known to be regulated by a variety of ...

Biophysical investigation of the dual binding surfaces of human transcription factors FOXO4 and p53.

Published in The FEBS journal

Cellular senescence is protective against external oncogenic stress, but its accumulation causes aging-related diseases. Forkhead box O4 (FOXO4) and p53 are human transcription factors known to promote senescence by interacting with each other and activating p21 transcription. Inhibition of the interaction is a strategy for inducing apoptosis of se...

Genome-wide identification and expression analysis of DREB genes in alfalfa ( Medicago sativa ) in response to cold stre...

Published in Plant Signaling & Behavior

Dehydration-responsive element-binding proteins (DREBs) belong to members of the AP2/ERF transcription factor superfamily, which has been reported to involve various abiotic-stress responses and tolerance in plants. However, research on the DREB -family is still limited in alfalfa ( Medicago sativa L.), a forage legume cultivated worldwide. The rec...