Parekh, Mohit Romano, Vito Hassanin, Kareem Testa, Valeria Wongvisavavit, Rintra Ferrari, Stefano Haneef, Atikah Willoughby, Colin Ponzin, Diego Jhanji, Vishal
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Published in
Journal of Tissue Engineering
The corneal endothelium is the posterior monolayer of cells that are responsible for maintaining overall transparency of the avascular corneal tissue via pump function. These cells are non-regenerative in vivo and therefore, approximately 40% of corneal transplants undertaken worldwide are a result of damage or dysfunction of endothelial cells. The...
Fernández-Costa, Juan M. Fernández-Garibay, Xiomara Velasco-Mallorquí, Ferran Ramón-Azcón, Javier
Published in
Journal of Tissue Engineering
Muscular dystrophies are a group of highly disabling disorders that share degenerative muscle weakness and wasting as common symptoms. To date, there is not an effective cure for these diseases. In the last years, bioengineered tissues have emerged as powerful tools for preclinical studies. In this review, we summarize the recent technological adva...
Yoon, Paul Sukwoo Del Piccolo, Nuala Shirure, Venktesh S. Peng, Yushuan Kirane, Amanda Canter, Robert J. Fields, Ryan C. George, Steven C. Gholami, Sepideh
Published in
Frontiers in Immunology
Colorectal cancer (CRC) is the third most common cancer and second leading cause of cancer-related death in the US. CRC frequently metastasizes to the liver and these patients have a particularly poor prognosis. The infiltration of immune cells into CRC tumors and liver metastases accurately predicts disease progression and patient survival. Despit...
Iacobazzi, Dominga Rapetto, Filippo Albertario, Ambra Swim, Megan M Narayan, Srinivas Skeffington, Katie Salih, Tasneem Alvino, Vincenza Valeria Madeddu, Paolo Ghorbel, Mohamed T
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Published in
Tissue engineering. Part A
The materials available for the right ventricular outflow tract (RVOT) reconstruction in patients with tetralogy of fallot (TOF)/pulmonary atresia come with the severe limitation of long-term degeneration and lack of growth potential, causing right ventricular dysfunction, aneurysm formation, and arrhythmias, thus necessitating several high-risk re...
Cercone, Marta Brown, Bryan N Stahl, Elizabeth C Mitchell, Lisa M Fortier, Lisa A Mohammed, Hussni O Ducharme, Norm G
Published in
Tissue engineering. Part A
Respiratory function in the horse can be severely compromised by arytenoid chondritis, or arytenoid chondropathy, a pathologic condition leading to deformity and dysfunction of the affected cartilage. Current treatment in cases unresponsive to medical management is removal of the cartilage, which can improve the airway obstruction, but predisposes ...
Zhu, Yi Wang, Dongzhi Yao, Xihao Wang, Mingming Zhao, Yahong Lu, Yuhua Wang, Zhiwei Guo, Yibing
Published in
Journal of biomaterials science. Polymer edition
Islet transplantation is considered as one of the promising treatment options for curing diabetes. However, the extracellular matrix (ECM) is destroyed during the process of islet isolation and extraction, which leads to decreased islet activity in vitro. ECM-based biomaterials which used to reconstruct the microenvironment of cells have been appli...
Li, Jing Zhu, Youming Li, Na Wu, Tao Zheng, Xianyu Heng, Boon chin Zou, Duohong Xu, Jianguang
Published in
Cell Transplantation
The lack of vasculogenesis often hampers the survivability and integration of newly engineered tissue grafts within the host. Autologous endothelial cells (ECs) are an ideal cell source for neovascularization, but they are limited by their scarcity, lack of proliferative capacity, and donor site morbidity upon isolation. The objective of this study...
Castillo-Henríquez, Luis Castro-Alpízar, Jose Lopretti-Correa, Mary Vega-Baudrit, José
Published in
International journal of molecular sciences
Innate and adaptive immune responses lead to wound healing by regulating a complex series of events promoting cellular cross-talk. An inflammatory response is presented with its characteristic clinical symptoms: heat, pain, redness, and swelling. Some smart thermo-responsive polymers like chitosan, polyvinylpyrrolidone, alginate, and poly(ε-caprola...
Moysidou, Chrysanthi-Maria Barberio, Chiara Owens, Róisín Meabh
Published in
Frontiers in Bioengineering and Biotechnology
Research in cell biology greatly relies on cell-based in vitro assays and models that facilitate the investigation and understanding of specific biological events and processes under different conditions. The quality of such experimental models and particularly the level at which they represent cell behavior in the native tissue, is of critical imp...
Santos, João Moschetta, Matteo Rodrigues, João Alpuim, Pedro Capasso, Andrea
Published in
Frontiers in Bioengineering and Biotechnology
Two-dimensional material (2DM) coatings exhibit complex and controversial interactions with biological matter, having shown in different contexts to induce bacterial cell death and contribute to mammalian cell growth and proliferation in vitro and tissue differentiation in vivo . Although several reports indicate that the morphologic and electronic...