Peplau, Emanuel De Rose, Francesco Reder, Sybille Mittelhäuser, Markus Scafetta, Giorgia Schwaiger, Markus Weber, Wolfgang A Bartolazzi, Armando Skerra, Arne D'Alessandria, Calogero
...
Published in
Thyroid : official journal of the American Thyroid Association
Background: The lack of facile methods for the specific characterization of malignant thyroid nodules makes the diagnosis of thyroid cancer (TC) challenging. Due to its restricted expression in such nodules, the cell-associated lectin galectin-3 (Gal3) has emerged as a marker for TC with growing interest for in vivo imaging as well as targeted radi...
Pozdeyev, Nikita Erickson, Timothy A Zhang, Lian Ellison, Kim Rivard, Christopher J Sams, Sharon Hirsch, Fred R Haugen, Bryan R French, Jena D
Published in
Thyroid : official journal of the American Thyroid Association
Background: Despite advances in targeted kinase inhibitor development for patients with medullary thyroid cancer (MTC), most patients develop resistance and would benefit from alternative approaches. Immune-based therapies are now considered for patients with progressive MTC. This study is the first comprehensive assessment of the immune milieu, im...
Papaleontiou, Maria Evron, Josh M Esfandiari, Nazanene H Reyes-Gastelum, David Ward, Kevin C Hamilton, Ann S Worden, Francis Haymart, Megan R
Published in
Thyroid : official journal of the American Thyroid Association
Background: Despite the excellent survival of most patients with differentiated thyroid cancer (DTC), recurrent and persistent disease remain major concerns for physicians and patients. However, studies on patient report of recurrent and persistent disease are lacking. Methods: Between February 1, 2017, and October 31, 2018, we surveyed eligible pa...
Chen, Tanya Gilfix, Brian M Rivera, Juan Sadeghi, Nader Richardson, Keith Hier, Michael P Forest, Véronique-Isabelle Fishman, Dina Caglar, Derin Pusztaszeri, Marc
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Published in
Thyroid : official journal of the American Thyroid Association
Background: Although the current gold standard for diagnosing thyroid nodule malignancy is ultrasound-guided fine-needle aspiration (FNA) cytology, about 20-25% of cytological evaluations are considered indeterminate for malignancy. This limitation has led to the emergence of next-generation sequencing panels, for example, ThyroSeq v3 (TSv3), which...
Kim, Ji Won Kim, Jeong Mi Choi, Mi Eun Kim, Seok-Ki Kim, Young-Mo Choi, Jeong-Seok
Published in
The Laryngoscope
This study was conducted to investigate the dose-response characteristics of radioiodine on salivary glands and to investigate the mechanism responsible for radioiodine-induced salivary glands toxicity. Twenty-four mice were divided into six groups: 0, 0.05, 0.10, 0.20, 0.40, and 0.80 mCi/20 g mouse, administered orally. Mortalities were noted 12 m...
Krcalova, Eva Horacek, Jiri Gabalec, Filip Zak, Pavel Dolezal, Jiri
Published in
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
Radioiodine (RAI) improves survival in patients with locally advanced or metastatic differentiated thyroid carcinoma (DTC). Although there has been an ongoing debate on RAI-induced salivary gland damage, published data have been inconsistent. Therefore, the purpose of our study was to compare salivary gland function in intermediate and high risk DT...
Liu, Jie Zheng, Xiong Liu, Hui
Published in
The journal of gene medicine
Accumulating evidence shows that circRNAs comprise a class of non-coding RNA exhibiting tremendous potential for cancer diagnosis and prognosis and they are also implicated in the pathogenesis of carcinogenesis. The present study aimed to investigate abnormally expressed circRNAs in thyroid cancer (TC). Five pairs of TC tissues and adjacent nornal ...
Wu, Shu-Ting Chi, Shun-Yu Wang, Pei-Wen Chen, Yung-Nien Yang, Yi-Ting Chen, Wen-Chieh Chen, Jung-Fu Chou, Chen-Kai
Published in
The Kaohsiung journal of medical sciences
Differentiated thyroid cancer (DTC) survivors are at increased risk of developing double primary malignancy (DPM). The aim of this study was to investigate clinicopathological characteristics and survival in DTC patients diagnosed with DPM. A total of 975 patients with DTC diagnosed between 2013 and 2017, treated, and followed at a medical center i...
Zhang, Xinyue Liu, Lina Chen, Yu Huang, Rui Liu, Bin
Published in
Head & neck
To evaluate the prognostic value of post-ablation whole-body scintigraphy (PAS) in children with thyroid cancer following 131 I therapy. A retrospective analysis of children with thyroid cancer who underwent remnant ablation was performed. PAS results were correlated with clinical and histopathologic characteristics of the primary tumor and compare...
Kumar, Praveen Damle, Nishikant Avinash Agarwala, Sandeep Dwivedi, Sada Nand Bal, Chandrasekhar
Published in
Journal of Pediatric Endocrinology and Metabolism
Objectives The amount of Iodine-131 to treat young patients with differentiated thyroid cancer (DTC) has not been established so far. The purpose of this study was to perform and compare blood dosimetry by “Hanscheid’s approach”and lesion dosimetry by “Maxon’s approach”. Methods Seventy-one DTC patients ≤21 years were given diagnostic activity of 7...
