Nakayoshi, Tomoki Kato, Koichi Fukuyoshi, Shuichi Takahashi, Ohgi Kurimoto, Eiji Oda, Akifumi
Published in
International journal of molecular sciences
Aspartic acid (Asp) residues are prone to nonenzymatic isomerization via a succinimide (Suc) intermediate. The formation of isomerized Asp residues is considered to be associated with various age-related diseases, such as cataracts and Alzheimer's disease. In the present paper, we describe the reaction pathway of Suc residue formation from Asp resi...
Machado, Susana Silva, Andreia De Sousa-Coelho, Ana Luísa Duarte, Isabel Grenho, Inês Santos, Bruno Mayoral-Varo, Victor Megias, Diego Sánchez-Cabo, Fátima Dopazo, Ana
...
Published in
Cancers
Therapy resistance is responsible for most relapses in patients with cancer and is the major challenge to improving the clinical outcome. The pseudokinase Tribbles homologue 2 (TRIB2) has been characterized as an important driver of resistance to several anti-cancer drugs, including the dual ATP-competitive PI3K and mTOR inhibitor dactolisib (BEZ23...
Yu, Yue Liu, Botao Tang, Xia Liu, Sheng Gao, Bing
Published in
Materials (Basel, Switzerland)
To reduce the thermal stress during the sublimation growth of 45 mm AlN single crystal, a tungsten sink was put on the top of the crucible lid. Numerical experiments showed that the radial temperature gradient was reduced due to the homogenization effect on temperature as a result of the sink. Therefore, this simple tungsten sink method has the pot...
Anjos Neto, Antônio Pereira dos Oliveira, Gustavo Roberto Fonseca Mello, Simone da Costa Silva, Marcio Souza da Gomes-Junior, Francisco Guilhien Novembre, Ana Dionisia da Luz Coelho Azevedo, Ricardo Antunes
ABSTRACT Spinach seeds are sensitive to high temperatures during germination and plant growth. It is known that seed priming with water or with seaweed extract (SWE) may enhance germination and seedling growth. The objective of this study was to evaluate the effects of seed priming with SWE (Ascophyllum nodosum) on the germination, seedling growth ...
Stråvik, Mia Barman, Malin Hesselmar, Bill Sandin, Anna Wold, Agnes E Sandberg, Ann-Sofie
Published in
Nutrients
Maternal diet during pregnancy and lactation may affect the propensity of the child to develop an allergy. The aim was to assess and compare the dietary intake of pregnant and lactating women, validate it with biomarkers, and to relate these data to physician-diagnosed allergy in the offspring at 12 months of age. Maternal diet during pregnancy and...
Nakano, Toshiki Wiegertjes, Geert
Published in
Marine drugs
Carotenoids, one of the most common types of natural pigments, can influence the colors of living organisms. More than 750 kinds of carotenoids have been identified. Generally, carotenoids occur in organisms at low levels. However, the total amount of carotenoids in nature has been estimated to be more than 100 million tons. There are two major typ...
Sun, Haoliang Lian, Xinxin Huang, Xiaoxue Hui, David Wang, Guangxin
Published in
Nanotechnology Reviews
This article studies two different sputtering methods for depositing Ag–Mo and Ag–Zr alloy films on single crystal silicon (Si), flexible polyimide (PI) and soda-lime glass substrates. The phase structure and the surface morphology of the Ag–Mo(Zr) alloy films were characterized by XRD, SEM and EDS. The effects of substrate properties and sputterin...
USUI, Haruki Tokuda, Makoto SUGIYAMA, Kazumasa Hoshina, Takuya Tsurumi, Takaaki Lebbou, Kheirreddine Yanase, Ikuo Takeda, Hiroaki
We present a possible method to reduce the anisotropy of the thermal stress generated on langasite-type La3Ta0.5Ga5.5O14 (LTG) piezoelectric crystals arising from the mismatch of the thermal expansion coefficients and Young’s moduli of the crystals and metals at high temperatures. To formulate this method, the thermal stresses of order-type langasi...
Burraco, Pablo Orizaola, Germán Monaghan, Pat Metcalfe, Neil B
Published in
Global change biology
Human activity is changing climatic conditions at an unprecedented rate. The impact of these changes may be especially acute on ectotherms since they have limited capacities to use metabolic heat to maintain their body temperature. An increase in temperature is likely to increase the growth rate of ectothermic animals, and may also induce thermal s...
Cui, Zhaoxing Hu, Xiaodong Dong, Shiyun Yan, Shixing Zhao, Xuan
Published in
Materials
The performance and service life of the nuclear emergency diesel engine shaft made of 12CrNi2 alloy steel is very important for the safety of nuclear power. Laser melting deposition (LMD) is a challenging camshaft-forming technology due to its high precision, rapid prototyping, and excellent parts performance. However, LMD is an unsteady process un...
