El-Newary, Samah A Aly, Mohamed S Hameed, Amal R Abd El Kotp, Mohamed S Youssef, Abdelghany A Ali, Naglaa A
Published in
Pharmaceutical biology
Cordia dichotoma Forst. (Boraginaceae) has potent pharmacological impact. Meanwhile, its effect on fertility is unclear. This study investigates the effect of Cordia fresh fruits hydroethanolic extract on fertility. 120 Wistar albino male rats were divided into four groups (n = 30). The first group was negative control, and the second, third, and f...
Federici, Silvia Goggi, Giovanni Quinton, Richard Giovanelli, Luca Persani, Luca Cangiano, Biagio Bonomi, Marco
Published in
Endocrine reviews
Delayed puberty (DP) defines a retardation of onset/progression of sexual maturation beyond the expected age from either a lack/delay of the hypothalamo-pituitary-gonadal axis activation or a gonadal failure. DP usually gives rise to concern and uncertainty in patients and their families, potentially affecting their immediate psychosocial well-bein...
Lucas-Herald, Angela K Touyz, Rhian M
Published in
The Canadian journal of cardiology
Androgens, including testosterone and its more potent metabolite, dihydrotestosterone, exert multiple actions in the body. Physiologically they play a critical role in male sex development. In addition, they influence vascular function including arterial vasodilation and mediation of myogenic tone. Androgens are produced from 9 weeks gestation in t...
Xu, You Han, Li Wei, Youdan Mao, Hongjing Yu, Zhenghe
Published in
Frontiers in Neuroscience
Objective Repetitive transcranial magnetic stimulation (rTMS) has a positive effect on patients with depressive disorder, while the underpinning molecular mechanism is unknown. Here, we aimed to investigate the effect of rTMS on serum levels of serum amyloid A (SAA) and testosterone in a real-world setting. Materials and methods In total, ninety-se...
Pillerová, Miriam Borbélyová, Veronika Pastorek, Michal Riljak, Vladimír Hodosy, Július Frick, Karyn M. Tóthová, L’ubomíra
Published in
Frontiers in Psychiatry
Anxiety disorders are one of the most prevalent mood disorders that can lead to impaired quality of life. Current treatment of anxiety disorders has various adverse effects, safety concerns, or restricted efficacy; therefore, novel therapeutic targets need to be studied. Sex steroid hormones (SSHs) play a crucial role in the formation of brain stru...
Wang, Na Zhang, Qian Sun, Wei Yang, Xiaoyu Huang, Hui Xu, Zuojun
Published in
Frontiers in Oncology
Background Interstitial lung disease (ILD) is the most common and potentially most devastating manifestation of SSc in pulmonary involvement. However, the mechanism for systemic sclerosis-associated ILD (SSc-ILD) is unclear. This work aims to explore the potential candidates for SSc-ILD upon whole exome sequencing (WES) and attempts to analyze the ...
Harrison, Tracy N H Chang, R Jeffrey
Published in
Clinical endocrinology
The mechanisms underlying ovarian dysfunction in polycystic ovary syndrome (PCOS) have not been definitively established. Our objective was to perform a detailed examination of ovarian responses to recombinant follicle-stimulating hormone (rFSH) in women with PCOS and controls. This prospective, crossover, dose-response study included three rFSH st...
Dhalech, Adeeba H. Corn, Caleb M. Mangale, Vrushali Syed, Fahim Condotta, Stephanie A. Richer, Martin J. Robinson, Christopher M.
Published in
Journal of Virology
Enteroviruses initiate infection in the gastrointestinal tract, and sex is often a biological variable that impacts pathogenesis. Previous data suggest that sex hormones can influence the intestinal replication of Coxsackievirus B3 (CVB3), an enterovirus in the Picornaviridae family. However, the specific sex hormone(s) that regulates intestinal CV...
Liang, Yun Huang, Xinshuang Fang, Li Wang, Mingjie Yu, Chunxiao Guan, Qingbo
Published in
Frontiers in Pharmacology
Iodoacetic acid (IAA) is one of the most common water disinfection byproducts (DBPs). Humans and animals are widely and continuously exposed to it. Many species of water DBPs are harmful to the reproductive system of organisms. Nevertheless, the potential effects of IAA exposure on testosterone and spermatogenesis in vivo remain ambiguous. Spermato...
Li, Yongchao Liu, Minghui Cui, Yu Zhu, Zewu Chen, Jinbo Zeng, Feng Gao, Meng Li, Yang Huang, Fang Chen, Hequn
...
Published in
Frontiers in Endocrinology
Purpose This study aimed to explore the relationship between serum testosterone levels and systemic immune-inflammation index (SII). Methods Complete SII and serum testosterone data of men over 20 years of age were retrieved from the 2011–2016 National Health and Nutrition Examination Survey to conduct a prevalence survey. To calculate SII, the pla...
