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Synteny-guided resolution of gene trees clarifies the functional impact of whole genome duplications

Whole genome duplications (WGD) have major impacts on the evolution of species, as they produce new gene copies contributing substantially to adaptation, isolation, phenotypic robustness, and evolvability. They result in large, complex gene families with recurrent gene losses in descendant species that sequence-based phylogenetic methods fail to re...

The nanos1 gene was duplicated in early Vertebrates and the two paralogs show different gonadal expression profiles in a...

Published in Scientific Reports

Nanos are RNA-binding proteins playing crucial roles in germ cell development and maintenance. Based on phylogenetic and synteny analyses, this study reveals that nanos1 gene has undergone multiple duplications and gene copies losses in Vertebrates. Chondrichthyan species display two nanos1 genes (named nanos1A/1B), which were both retrieved in som...

The nanos1 gene was duplicated in early Vertebrates and the two paralogs show diferent gonadal expression profles in a s...

Nanos are RNA-binding proteins playing crucial roles in germ cell development and maintenance. Based on phylogenetic and synteny analyses, this study reveals that nanos1 gene has undergone multiple duplications and gene copies losses in Vertebrates. Chondrichthyan species display two nanos1 genes (named nanos1A/1B), which were both retrieved in som...

Global gene expression in muscle from fasted/refed trout reveals up-regulation of genes promoting myofibre hypertrophy b...

Published in BMC Genomics

BackgroundCompensatory growth is a phase of rapid growth, greater than the growth rate of control animals, that occurs after a period of growth-stunting conditions. Fish show a capacity for compensatory growth after alleviation of dietary restriction, but the underlying cellular mechanisms are unknown. To learn more about the contribution of genes ...

Evolutionary history of glucose-6-phosphatase encoding genes in vertebrate lineages: towards a better understanding of t...

Published in BMC Genomics

BackgroundGlucose-6-phosphate (G6pc) is a key enzyme involved in the regulation of the glucose homeostasis. The present study aims at revisiting and clarifying the evolutionary history of g6pc genes in vertebrates.Resultsg6pc duplications happened by successive rounds of whole genome duplication that occurred during vertebrate evolution. g6pc dupli...