Non-alcoholic fatty liver disease is a multifaceted disease that progresses through multiple phases; it involves metabolic as well as structural changes. These alterations can be measured directly or indirectly through blood, non-invasive imaging, and/or tissue analyses. While some studies have evaluated the correlations between two sets of measure...
The Climate Security Observatory (CSO) is an online platform for stakeholder decision-making that provides access to a range of global analyses related to climate and security. The CSO is based on an integrated climate security framework that helps understand the complexity of the climate-security interface. As part of the CSO Methods Paper Series,...
Published in Frontiers in Cardiovascular Medicine
Objective Marginalized communities shoulder a disproportionate burden of cardiovascular disease (CVD) driven by concentrated neighborhood social risk factors. We provide a case study of systems science application to address geographic CVD health disparities at the community level – informing the science of CVD health disparities research. Methods ...
Published in Journal of biomolecular structure & dynamics
Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disease leading to inflammation, cartilage cell death, synoviocyte proliferation, and increased and impaired differentiation of osteoclasts and osteoblasts leading to joint erosions and deformities. Transcriptomics, proteomics, and metabolomics datasets were analyzed to identify the critica...
Published in Environmental Research Letters
The timing of rice planting has a profound influence on the productivity of the rice-wheat cropping pattern in the Indo-Gangetic Plains (IGP), a system that provides the foundation for food security in South Asia. Nevertheless, strategies for adaptive rice planting in a rapidly changing climate are not well established. In this ex-ante analysis, re...
Published in The Veterinary record
Systems analysis is widely recommended for patient safety investigations in medicine, but the method is poorly described in the veterinary literature. Anaesthetic safety incidents were discussed in debriefs and then reported on standardised forms. Investigators performed informal interviews with team members involved in case management and interrog...
The timing of rice planting has a profound influence on the productivity of the rice-wheat cropping pattern in the Indo-Gangetic Plains (IGP), a system that provides the foundation for food security in South Asia. Nevertheless, strategies for adaptive rice planting in a rapidly changing climate are not well established. In this ex-ante analysis, re...
Published in Frontiers in Environmental Science
The social cost of carbon (SCC) is estimated by integrated assessment models (IAMs) and is widely used by government agencies to value climate policy impacts. Although there is an ongoing debate about obtained numerical estimates and related uncertainties, little attention has been paid so far to the SCC calculation method itself. This work attempt...
Published in Ergonomics
Incident reporting systems are a fundamental component of safety management, however, most systems used in practice are not aligned with contemporary accident causation models. This article presents an analysis of a National Incident Dataset (NID) for adverse incidents occurring in the Australian Led Outdoor Activity (LOA) sector. The aim was to in...
Individual differences in the responsiveness of the brain to transcranial electrical stimulation (tES) are increasingly demonstrated by the large variability in the effects of tES. Anatomically detailed computational brain models have been developed to address this variability; however, static brain models are not “realistic” in accounting for the ...
