Assunção, Helena Jesus, Diogo Larosa, Maddalena Henriques, Carla Matos, Ana Le Guern, Véronique Rubiño, Francisco da Silva, José A P Rua-Figueroa, Iñigo Costedoat-Chalumeau, Nathalie
...
Published in
Rheumatology (Oxford, England)
To derive and validate a definition of low disease activity (LDA) for SLE based on the SLE Disease Activity Score (SLE-DAS), in a real-life multicentre cohort of SLE patients. Derivation was conducted using data from a monocentric cohort of SLE (Portugal), and validation was performed in a multicentre cohort (Italy, France and Spain). The Lupus Low...
Song, Wentao Chu, Shujuan Yang, Kai Sun, Xilong Xia, Haifa Mei, Chunli Zhao, Yin Wu, Jing
Published in
Journal of cardiothoracic and vascular anesthesia
Systemic lupus erythematosus (SLE) accounts for the largest portion of connective tissue disease-associated pulmonary arterial hypertension (PAH) in Asian countries, especially in China, and SLE-PAH poses multiple challenges during pregnancy and delivery. Patients with SLE-PAH tend to have lower survival rates and worse quality of life than other s...
Zhao, Like Hu, Xianda Xiao, Fei Zhang, Xuan Zhao, Lidan Wang, Min
Published in
Frontiers in Immunology
Nucleic acid autoantibodies, increase type I interferon (IFN-α) levels, and immune cell hyperactivation are hallmarks of systemic lupus erythematosus (SLE). Notably, immune cell activation requires high level of cellular energy that is predominately generated by the mitochondria. Mitochondrial reactive oxygen species (mROS), the byproduct of mitoch...
Wang, Yimin Su, Wenge Li, Yunlun Yuan, Jie Yao, Minghao Su, Xiaoyi Wang, Yifei
Published in
Frontiers in Immunology
Background Accumulating evidence supports the predisposition of systemic lupus erythematosus (SLE) to atherosclerosis (AS). However, the common pathogenesis of these two diseases remains unclear. This study aimed to explore the mechanisms of SLE complicated by AS. Methods Gene expression profiles of SLE (GSE50772) and AS (GSE100927) were downloaded...
Wu, Qian Liu, Yang Wang, Wei Zhang, Yu Liu, Kui Chen, Song-Hua Chen, Bin
Published in
Frontiers in Immunology
Background Systemic lupus erythematosus (SLE) patients are particularly susceptible to infections, such as pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB). This meta-analysis aimed to determine the incidence and prevalence of tuberculosis (TB) in SLE patients. Methods The Web of Science, PubMed, Cochrane Library, and Chinese Nat...
Ni, Jiajia Li, Jingyi Wang, Yuyao Guan, Liying Lin, Haiyan Zhang, Li Zhang, Haiqing
Published in
Frontiers in Endocrinology
Purpose The aim of this study included determining the prevalence of hypothyroidism in patients with systemic lupus erythematosus (SLE), clarifying the clinical characteristics of SLE patients with hypothyroidism, and identifying the relationship between hypothyroidism and SLE-related organic damage. Another purpose was to analyze the relationship ...
Yang, Beibei Dong, Jiayu Bian, Haifeng Lu, Haimin Bin, Duan Tang, Shaochun Song, Yaqiong Lu, Hongbin
Published in
Nanomaterials (Basel, Switzerland)
A self-healing epoxy coating is creatively prepared by employing expired cefalexin loaded into mesoporous silica nanomaterials (MSNs) for corrosion protection of 304 stainless steel (304SS). A series of physical characterizations, including transmission electron microscopy (TEM), Fourier transform infrared (FTIR) spectrometer, and N2 adsorption-des...
Wang, Zhuang Heid, Bettina Lu, Ran Sachdeva, Mohit Edwards, Michael R. Ren, JingJing Cecere, Thomas E. Khan, Deena Jeboda, Taschua Kirsch, David G.
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Published in
Frontiers in Genetics
Dysregulated miRNAs have been implicated in the pathogenesis of systemic lupus erythematosus (SLE). Our previous study reported a substantial increase in three miRNAs located at the miR-183-96-182 cluster (miR-183C) in several autoimmune lupus-prone mice, including MRL/lpr and C57BL/6-lpr (B6/lpr). This study reports that in vitro inhibition of miR...
Pan, Quanren Walls, Andrew F. Pan, Qingjun
Published in
Frontiers in Immunology
Blomjous, Birgit S Gajadin, Gayle R S Voskuyl, Alexandre E Falzon, Louise Hoving, Jan L Bultink, Irene E M Ter Wee, Marieke M
Published in
Rheumatology (Oxford, England)
This systematic review assessed which variables are associated with or are predictors for work participation outcomes in patients with systematic lupus erythematosus (SLE). A literature search using MEDLINE, The Cochrane Library, Embase and CINAHL was conducted to identify all studies published from inception (1947) to June 2021 on factors related ...
