Published in Frontiers in Physics
One of the most surprising mechanisms to explain the symmetry breaking phenomenon linked to pattern formation is known as Turing instabilities. These patterns are self-organising spatial structures resulting from the interaction of at least two diffusive species in specific conditions. The ideas of Turing have been used extensively in the specialis...
Published in Frontiers in Microbiology
Published in Frontiers in Bioengineering and Biotechnology
Filamentous fungi are highly productive cell factories, many of which are industrial producers of enzymes, organic acids, and secondary metabolites. The increasing number of sequenced fungal genomes revealed a vast and unexplored biosynthetic potential in the form of transcriptionally silent secondary metabolite biosynthetic gene clusters (BGCs). V...
Published in Microorganisms
Genistein, a nutraceutical isoflavone, has various pharmaceutical and biological activities which benefit human health via soy-containing food intake. This study aimed to construct Saccharomyces cerevisiae to produce genistein from sugar via a modular engineering strategy. In the midstream module, various sources of chalcone synthases and chalcone ...
Celične tovarne se vedno znova izkazujejo ne le za koristen, ampak pogosto tudi bistveni del najrazličnejših vej industrije. Njihova uporabnost sega tako na področje medicine in farmacije, zelene energije, kot izdelave mnogih drugih produktov z visoko dodano vrednostjo. Sevi, ki jih najdemo v naravi v veliki večini primerov sami po sebi ne zadostuj...
Published in Frontiers in Microbiology
The genus Streptomyces is known to harbor numerous biosynthetic gene clusters (BGCs) of potential utility in synthetic biology applications. However, it is often difficult to link uncharacterized BGCs with the secondary metabolites they produce. Proteomining refers to the strategy of identifying active BGCs by correlating changes in protein express...
Published in Frontiers in Chemical Engineering
Flavonoids, a major group of secondary metabolites in plants, are promising for use as pharmaceuticals and food supplements due to their health-promoting biological activities. Industrial flavonoid production primarily depends on isolation from plants or organic synthesis, but neither is a cost-effective or sustainable process. In contrast, recombi...
Published in Frontiers in Environmental Science
This study explored public attitudes towards developing synthetic biology solutions for environmental problems: 1) invasive pest management, 2) endangered species conservation, 3) bioremediation of waterways, and 4) coral reef restoration. A sample of 4,593 Australians were surveyed online. Results showed that public support for a synthetic biology...
Published in Frontiers in Chemistry
Although organic UV-filters are extensively used in cosmetics to protect consumers from the deleterious effects of solar UV radiation-exposure, they suffer from some major drawbacks such as their fossil origin and their toxicity to both humans and the environment. Thus, finding sustainable and non-toxic UV-filters is becoming a topic of great inter...
Published in Protein & cell
Cell therapy approaches that employ engineered mammalian cells for on-demand production of therapeutic agents in the patient's body are moving beyond proof-of-concept in translational medicine. The therapeutic cells can be customized to sense user-defined signals, process them, and respond in a programmable and predictable way. In this paper, we in...
