Li, Ge Zhang, Chuang Liang, Wei Zhang, Yanbing Shen, Yunheng Tian, Xinhui
Published in
Pharmaceutical biology
Berberine (BBR) is used to treat diarrhoea and gastroenteritis in the clinic. It was found to have anticolon cancer effects. To study the anticolon cancer mechanism of BBR by connectivity map (CMAP) analysis. CMAP based mechanistic prediction was conducted by comparing gene expression profiles of 10 μM BBR treated MCF-7 cells with that of clinical ...
Mansoor, M. A. Hamzah, K. Naeem, R. Zubir, M. N. B. M. Yahaya, N. A. Yusof, F. B. Rozali, S. B. Aspanut, Z. B. Ming, H. N.
Published in
Russian Journal of Inorganic Chemistry
AbstractIn extension to our previous work, studies have been conducted to illustrate the effect of incorporation of Co2O3 on photo-conversion efficiency of Mn2O3–4TiO2 composite thin films. Therefore, the bimetallic crystal [Mn2Ti4(TFA)8(THF)6(OH)4(O)2]⋅0.4THF (1) was mixed with Co(OAc)2 to fabricate Mn2O3–Co2O3–4TiO2 (MCT) thin films via aerosol-a...
Feng, Xiaoxuan Liu, Shuai Wang, Yang Zhang, Yulin Sun, Lingxiao Li, Haibo Wang, Chunlei Liu, Yingmei Cao, Bin
Published in
Frontiers in Microbiology
Colistin-resistant (Col-R) bacteria are steadily increasing, and are extremely difficult to treat. New drugs or therapies are urgently needed to treat infections caused by these pathogens. Combination therapy with colistin and other old drugs, is an important way to restore the activity of colistin. This study aimed to investigate the activity of c...
Fischer, Thorben Winter, Inga Drumm, Robert Schneider, Marc
Published in
Pharmaceutics
The transport of macromolecular drugs such as oligonucleotides into the lungs has become increasingly relevant in recent years due to their high potency. However, the chemical structure of this group of drugs poses a hurdle to their delivery, caused by the negative charge, membrane impermeability and instability. For example, siRNA to reduce tumour...
Guo, Xu Ai, Shasha Yang, Dan Zhao, Lei Ding, Hanming
Published in
Environmental technology
The integration of two different advanced oxidation processes can not only avoid their individual shortcomings but also utilize the synergistic effects between them. Herein, CoFe2O4 modified g-C3N4 composite ([email protected]) was synthesized and used for building a novel coupled system, in which two processes of visible light-activated photocatalysi...
Cui, Wenjing Wang, Jiang Sagala, Jia, Meilin
Published in
Russian Journal of Physical Chemistry A
AbstractThe base-free synthesis of imines from amines and aliphatic alcohols over Au–Pd alloy catalysts under ambient conditions was developed. A series of Au–Pd/ZrO2 bimetallic catalysts with varying metal loadings and Au : Pd molar ratios were prepared and their catalytic performance was investigated. The 3.0 wt % Au–Pd/ZrO2 alloy catalyst with A...
Nehdi, Atef Samman, Nosaibah Mashhour, Abdullah Alhallaj, Alshaimaa Trivilegio, Thadeo Gul, Sheraz Reinshagen, Jeanette Alaskar, Ahmed Gmati, Gamal Abuelgasim, Khadega A.
...
Published in
Frontiers in Oncology
Drug repositioning is a promising and powerful innovative strategy in the field of drug discovery. In this study, we screened a compound-library containing 800 Food and Drug Administration approved drugs for their anti-leukemic effect. All screening activities made use of human peripheral blood mononuclear cells (PBMCs), isolated from healthy or le...
Pankratov, A. A. Musaev, R. A. Badina, S. V.
Published in
Studies on Russian Economic Development
Abstract—The article discusses modern approaches to measuring, evaluating and predicting cluster effects, proposes their classification, taking into account directly the effects of the activity of cluster formations, as well as effects outside the cluster formations—potential cluster effects. It offers an integral definition of the concept of “clus...
Gong, Feirong Ma, Jian-Chao Jia, Jianguo Li, Fa-Zhan Wu, Jiao-Lan Wang, Shanfeng Teng, Xin Cui, Zhong-Kai
Published in
Drug Delivery
Curcumin (1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) is a potent anticancer drug with versatile biological activities, while the clinical translation of curcumin is severely limited due to its hydrophobicity, rapid elimination, and metabolism in the blood circulation. Herein, we aim to unravel the potential of curcumin as a synerg...
Hu, Zengchun Cheng, Chuandong Wang, Yue Chen, Tianrui Tu, Junhong Niu, Chaoshi Xing, Rong Wang, Yang Xu, Yinghui
Published in
Frontiers in Oncology
Neuroblastoma is the most common extracranial neuroendocrine tumor in childhood. Although many studies have tried to find effective treatments, there are still numerous limitations in current clinical targeted therapy. So, it is important to find new therapeutic targets and strategies from a new perspective. Our previous study reported that the and...
