Liu, Ai-Mei Chen, Bo-Li Yu, Ling-Tai Liu, Tao Shi, Ling-Ling Yu, Pan-Pan Qu, Yi-Bo So, Kwok-Fai Zhou, Li-Bing
Published in
Neural regeneration research
Multiple types of stem cells have been proposed for the treatment of spinal cord injury, but their comparative information remains elusive. In this study, a rat model of T10 contusion spinal cord injury was established by the impactor method. Human umbilical cord-derived mesenchymal stem cells (UCMSCs) or human adipose tissue-derived mesenchymal st...
Stupin, Victor Manturova, Natalia Silina, Ekaterina Litvitskiy, Petr Vasin, Vitaly Artyushkova, Elena Ivanov, Alexander Gladchenko, Mikhail Aliev, Salekh
Published in
Journal of Experimental Pharmacology
Purpose To study the effects of inflammation on the healing process of rats’ acute skin wounds during treatment with different injections. Methods The study was carried out on Wistar rats, on which square wounds were simulated in the back region. Four groups of wounds were studied. On the day of the simulation (day 0), solutions of the drugs were i...
Chaigne, Agathe Labouesse, Céline White, Ian J. Agnew, Meghan Hannezo, Edouard Chalut, Kevin J. Paluch, Ewa K.
Published in
Developmental Cell
Cell division has been implicated in fate decisions in many stem cells. Chaigne et al. show that mouse embryonic stem cells exit naive pluripotency after cell division. Naive sister cells remain connected by cytoplasmic bridges after division, and bridge abscission promotes naive pluripotency exit.
Biedzinski, Stefan Agsu, Gökçe Vianay, Benoit Delord, Marc Blanchoin, Laurent Larghero, Jerome Faivre, Lionel Théry, Manuel Brunet, Stéphane
Hematopoietic stem and progenitor cells (HSPC) can differentiate into all hematopoietic lineages to support hematopoiesis. Cells from the myeloid and lymphoid lineages fulfill distinct functions with specific shapes and intra-cellular architectures. The role of cytokines in the regulation of HSPC differentiation has been intensively studied but our...
Mahiddine, Feriel Yasmine Kim, Jin Wook Qamar, Ahmad Yar Ra, Jeong Chan Kim, Soo Hyun Jung, Eun Joong Kim, Min Jung
Published in
Animals : an Open Access Journal from MDPI
Simple Summary Mesenchymal stem cells and their derivatives are used in clinical studies for their anti-apoptotic, anti-oxidant, immunomodulatory, and regenerative properties. Their use in reproductive medicine is increasing as they have been proved to be beneficial for infertility treatment. Mesenchymal stem cells can secrete factors that influenc...
Wang, Lihui Chen, Ruping Li, Guo Wang, Zhiguo Liu, Jun Liang, Ying Liu, Jun-Ping
Published in
Cell metabolism
Tissue stem cells undergo premature senescence under stress, promoting age-related diseases; however, the associated mechanisms remain unclear. Here, we report that in response to radiation, oxidative stress, or bleomycin, the E3 ubiquitin ligase FBW7 mediates cell senescence and tissue fibrosis through telomere uncapping. FBW7 binding to telomere ...
Sanz-Garcia, Andres Sodupe-Ortega, Enrique Pernía-Espinoza, Alpha Shimizu, Tatsuya Escobedo-Lucea, Carmen
Published in
Polymers
Three-dimensional (3D) bioprinting promises to be essential in tissue engineering for solving the rising demand for organs and tissues. Some bioprinters are commercially available, but their impact on the field of Tissue engineering (TE) is still limited due to their cost or difficulty to tune. Herein, we present a low-cost easy-to-build printhead ...
Paek, Soung-Chu Min, Sae Kyung Park, Jun-Beom
Published in
Biomedical Reports
Platelet-derived growth factor-BB (PDGF-BB) is a potent mitogenic, angiogenic and chemoattractant, and is one of the most abundant growth factors in platelet-derived products. The goal of the present study was to examine the effects of PDGF-BB on cellular morphology and cellular viability using 3D stem cell cultures. On day 1, spheroids formed well...
Baldassari, Simona Musante, Ilaria Iacomino, Michele Zara, Federico Salpietro, Vincenzo Scudieri, Paolo
Published in
Frontiers in Cell and Developmental Biology
Neurodevelopmental disorders (NDDs) are a group of disorders in which the development of the central nervous system (CNS) is disturbed, resulting in different neurological and neuropsychiatric features, such as impaired motor function, learning, language or non-verbal communication. Frequent comorbidities include epilepsy and movement disorders. Ad...
Talaat, Wael Aryal AC, Smriti Al Kawas, Sausan Samsudin, A B Rani Kandile, Nadia G Harding, David R K Ghoneim, Mohamed M Zeiada, Waleed Jagal, Jayalakshmi Aboelnaga, Ahmed
...
Published in
International Journal of Nanomedicine
Purpose Several scaffolds and cell sources are being investigated for cartilage regeneration. The aim of the study was to prepare nanocellulose-based thermosensitive injectable hydrogel scaffolds and assess their potential as 3D scaffolds allowing the chondrogenic differentiation of embedded human dental pulp stem and progenitor cells (hDPSCs). Mat...
