Differences between small and large intestine and liver in the inducibility of microsomal enzymes in response to stimula...
Published in Biochemical Pharmacology
Rats were fed either sodium phenobarbitone (PB) or betanaphthoflavone (BNF) for seven days. Deethylation of 7-ethoxyresorufin (7ERR) and 7-ethoxycoumarin (7EC) was measured in small and large intestine and liver, and cytochrome P-450 in liver. Our semi-purified diet was shown to produce minimal levels of intestinal deethylation activity. BNF was ad...
