Suvorov, Alexander Pilsner, J. Richard Naumov, Vladimir Shtratnikova, Victoria Zheludkevich, Anna Gerasimov, Evgeny Logacheva, Maria Sergeyev, Oleg
Published in
International Journal of Molecular Sciences
Advanced paternal age at fertilization is a risk factor for multiple disorders in offspring and may be linked to age-related epigenetic changes in the father’s sperm. An understanding of aging-related epigenetic changes in sperm and environmental factors that modify such changes is needed. Here, we characterize changes in sperm small non-coding RNA...
Punga, Tanel Darweesh, Mahmoud Akusjärvi, Göran
Published in
Viruses
Human adenoviruses (HAdVs) are common pathogens causing a variety of respiratory, ocular and gastrointestinal diseases. To accomplish their efficient replication, HAdVs take an advantage of viral small non-coding RNAs (sncRNAs), which have multiple roles during the virus lifecycle. Three of the best-characterized HAdV sncRNAs; VA RNA, mivaRNA and M...
Sellem, Eli Marthey, Sylvain Rau, Andrea Jouneau, Luc Bonnet, Aurelie Perrier, Jean-Philippe Fritz, Sébastien Le Danvic, Chrystelle Boussaha, Mekki Kiefer, Hélène
...
Published in
Epigenetics & Chromatin
BackgroundMature sperm carry thousands of RNAs, including mRNAs, lncRNAs, tRNAs, rRNAs and sncRNAs, though their functional significance is still a matter of debate. Growing evidence suggests that sperm RNAs, especially sncRNAs, are selectively retained during spermiogenesis or specifically transferred during epididymis maturation, and are thus del...
Esposito, S Aversano, R Bradeen, J M Di Matteo, A Villano, C Carputo, D
Published in
Plant biology (Stuttgart, Germany)
Among wild species used in potato breeding, Solanum commersonii displays the highest tolerance to low temperatures under both acclimated (ACC) and non-acclimated (NACC) conditions. It is also the first wild potato relative with a known whole genome sequence. Recent studies have shown that abiotic stresses induce changes in the expression of many sm...
Sarropoulou, Elena Kaitetzidou, Elizabet Papandroulakis, Nikos Tsalafouta, Aleka Pavlidis, Michalis
Published in
Frontiers in Genetics
During early animal ontogenesis, a plethora of small non-coding RNAs (sncRNAs) are greatly expressed and have been shown to be involved in several regulatory pathways vital to proper development. The rapid advancements in sequencing and computing methodologies in the last decade have paved the way for the production of sequencing data in a broad ra...
Rosani, Umberto Shapiro, Maxwell Venier, Paola Allam, Bassem
Published in
Viruses
Bivalve mollusks thrive in environments rich in microorganisms, such as estuarine and coastal waters, and they tend to accumulate various particles, including viruses. However, the current knowledge on mollusk viruses is mainly centered on few pathogenic viruses, whereas a general view of bivalve-associated viromes is lacking. This study was design...
Blake, Georgina Emma Tallulah
Exposure to environmental stressors can impact our health and that of future generations even when they are not similarly exposed. How disease risk is inherited is unclear. My thesis focuses on a mouse model of transgenerational inheritance in which folate metabolism is disrupted by a mutation in Methionine synthase reductase ($\it{Mtrr^gt}$). Rema...
Chuang, Tsai-Der Xie, Yeming Yan, Wei Khorram, Omid
Published in
Fertility and sterility
Objective To determine the expression profile of small non-coding RNAs (sncRNAs) which have not been investigated to date in leiomyoma. Design Laboratory based investigation. Setting Academic center. Patients Women undergoing hysterectomy for benign indications. Intervention Next generation sequencing and screening of sncRNA database with confirmat...
Gao, Xin Tyagi, Rahul Magrini, Vincent Ly, Amy Jasmer, Douglas P Mitreva, Makedonka
Published in
RNA biology
The intestine of parasitic nematodes has proven an important target for therapies aimed at prevention and treatment of diseases caused by these pathogens in humans, animals and plants. We have developed a unique research model with the intestine of Ascaris suum, the large round worm of swine and humans, that will enhance biological research on this...
SELLEM, Eli Marthey, Sylvain Kiefer, Helene Le Danvic, Chrystelle Bonnet, Aurelie Perrier, Jean-Philippe Jouneau, Luc Rau, Andréa Jammes, Hélène Schibler, Laurent
...
Le spermatozoïde a longtemps été considéré comme un taxi, protégeant et transportant son patrimoine génétique jusqu’à la délivrance dans l’ovocyte. Mais depuis quelques années de nouveaux arguments, autour des mécanismes épigénétiques, tels que les petits ARN non codants (sncRNA), proposent une nouvelle vision de la fonction du spermatozoïde par so...
