Relaix, F. Bencze, M. Borok, M. J. Der Vartanian, A. Gattazzo, F. Mademtzoglou, D. Perez-Diaz, S. Prola, A. Reyes-Fernandez, P. C. Rotini, A.
...
Published in
Nature Communications
Skeletal muscle has a remarkable regenerative capacity, which can largely be attributed to resident muscle stem cells (MuSCs). Here, the authors review the molecular mechanisms regulating MuSC quiescence, activation and proliferation, how these processes are regulated by the stem cell niche, and the role of MuSCs in neuromuscular diseases.
Le Bacquer, Olivier Lanchais, Kassandra Combe, Kristell Van Den Berghe, Loïc Walrand, Stéphane
Published in
Journal of cellular physiology
Sarcopenia is an age-related loss of muscle mass associated with changes in skeletal muscle protein homeostasis due to lipid accumulation and anabolic resistance; changes that are also commonly described in obesity. Activation of the endocannabinoid system is associated with the development of obesity and insulin resistance, and with the perturbed ...
Smith, Benjamin A. Gelles, Jeff Goode, Bruce L.
Published in
Methods in Enzymology
The actin cytoskeleton is very dynamic and highly regulated by multiple associated proteins in vivo. Understanding how this system of proteins functions in the processes of actin network assembly and disassembly requires methods to dissect the mechanisms of activity of individual factors and of multiple factors acting in concert. The advent of sing...
Graham, Zachary A. DeBerry, Jennifer J. Cardozo, Christopher P. Bamman, Marcas M.
Published in
Physiological Reports
SS‐31 is an efficacious treatment for many pre‐clinical models of muscle disuse. We show that daily injections of SS‐31 were not able to prevent muscle or body mass losses 14 d after an acute contusion SCI in mice.
Matarneh, Sulaiman K. Silva, Saulo L. Gerrard, David E.
Fresh meat quality is greatly determined through biochemical changes occurring in the muscle during its conversion to meat. These changes are key to imparting a unique set of characteristics on fresh meat, including its appearance, ability to retain moisture, and texture. Skeletal muscle is an extremely heterogeneous tissue composed of different ty...
Lieber, Richard L. Domenighetti, Andrea A.
Published in
Frontiers in Physiology
Akashi, Shiori Morita, Akihito Mochizuki, Yusuke Shibuya, Fuka Kamei, Yasutomi Miura, Shinji
Published in
Nutrients
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is expressed in skeletal muscles and regulates systemic metabolism. Thus, nutraceuticals targeting skeletal muscle PGC-1α have attracted attention to modulate systemic metabolism. As auraptene contained in citrus fruits promotes lipid metabolism and improves mitochondrial respirat...
De Sanctis, Paola Filardo, Giuseppe Abruzzo, Provvidenza Maria Astolfi, Annalisa Bolotta, Alessandra Indio, Valentina Di Martino, Alessandro Hofer, Christian Kern, Helmut Löfler, Stefan
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Published in
International journal of molecular sciences
In a previous study, the whole transcriptome of the vastus lateralis muscle from sedentary elderly and from age-matched athletes with an exceptional record of high-intensity, life-long exercise training was compared-the two groups representing the two extremes on a physical activity scale. Exercise training enabled the skeletal muscle to counteract...
McBean, Sally E. Church, Jarrod E. Thompson, Brett K. Taylor, Caroline J. Fitton, J. H. Stringer, Damien N. Karpiniec, Sam S. Park, Ah Y. van der Poel, Chris
Published in
Physiological Reports
Fucoidan is a complex polysaccharide found in brown seaweed. While fucoidan has many bioactive properties, here we show that in mice, 4 weeks of supplementation with a novel blend of fucoidan species increased both size and strength of skeletal muscle.
Rovina, Rafael L. da Rocha, Alisson L. Marafon, Bruno B. Pauli, José R. de Moura, Leandro P. Cintra, Dennys E. Ropelle, Eduardo R. da Silva, Adelino S. R.
Published in
Frontiers in Physiology
The nuclear receptor subfamily 1, group D member 1 ( Nr1d1) , plays a role in the skeletal muscle’s oxidative capacity, mitochondrial biogenesis, atrophy genes, and muscle fiber size. In light of the effects of physical exercise, the present study investigates the acute response of Nr1d1 and genes related to atrophy and mitochondrial biogenesis on ...