Mulchandani, Ranya Brown, Ben Brooks, Tim Semper, Amanda Machin, Nicholas Linley, Ezra Borrow, Ray Wyllie, David Taylor-Philips, Sian Jones, Hayley
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Published in
Journal of Clinical Virology
Dried blood spot samples (DBS) provide an alternative sample type to venous blood samples for antibody testing. DBS are used by NHS for diagnosing HCV and by PHE for large scale HIV and Hepatitis C serosurveillance; the applicability of DBS based approaches to SARS-CoV-2 antibody detection is uncertain. The study aimed to compare antibody detection...
Banjar, Ayman Al-Tawfiq, Jaffar A. Alruwaily, Amaal Alserehi, Haleema Al-Qunaibet, Ada Alaswad, Rehab Almutlaq, Hind Almudaiheem, Abdullah Khojah, Abdullah T. Alsaif, Faisal
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Published in
International Journal of Infectious Diseases
Background Serologic testing provides better understanding of SARS-CoV-2 prevalence and its transmission. This study is the first investigation of the prevalence of antibodies to SARS-CoV-2 among blood donors in Saudi Arabia. Objective To estimate the seroprevalence of anti-SARS-CoV-2 antibodies among blood donors in Saudi Arabia during the early p...
Kohn, Michael A.
Published in
Annals of Emergency Medicine
Willette, Auriel A. Willette, Sara A. Wang, Qian Pappas, Colleen Klinedinst, Brandon S. Le, Scott Larsen, Brittany Pollpeter, Amy Li, Tianqi Brenner, Nicole
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Published in
medRxiv
Background: Many risk factors have emerged for novel 2019 coronavirus disease (COVID-19). It is relatively unknown how these factors collectively predict COVID-19 infection risk, as well as risk for a severe infection (i.e., hospitalization). Methods: Among aged adults (69.3 ± 8.6 years) in UK Biobank, COVID-19 data was downloaded for 4,510 partici...
McGuire, Sarayna S Klassen, Aaron B Heywood, John Sztajnkrycer, Matthew D
Published in
Prehospital and disaster medicine
Although first responders (FRs) represent a high-risk group for exposure, little information is available regarding their risk of coronavirus disease 2019 (COVID-19) infection. The purpose of the current study was to determine the serological prevalence of past COVID-19 infection in a cohort of municipal law enforcement (LE) and firefighters (FFs)....
McPherson, Tristan D Ghinai, Isaac Binder, Alison M Freeman, Brandi D Hoskin Snelling, Chantel Hunter, Jennifer C Anderson, Kristin M Davenport, Polly Rudd, Deborah L Zafer, Mujeeb
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Published in
Public health reports (Washington, D.C. : 1974)
Widespread global transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing coronavirus disease 2019 (COVID-19), continues. Many questions remain about asymptomatic or atypical infections and transmission dynamics. We used comprehensive contact tracing of the first 2 confirmed patients in Illinois with COVID-19...
Van Honacker, Eveline Coorevits, Liselotte Boelens, Jerina Verhasselt, Bruno Van Braeckel, Eva Bauters, Fré De Bus, Liesbet Schelstraete, Petra Willems, Jef Vandendriessche, Stien
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Published in
Acta Clinica Belgica
Background: Molecular detection of SARS-CoV-2 in respiratory samples is the gold standard for COVID-19 diagnosis but it has a long turnaround time and struggles to detect low viral loads. Serology could help to diagnose suspected cases which lack molecular confirmation. Two case reports are presented as illustration. Objectives: The aim of this stu...
Staines, Henry M. Kirwan, Daniela E. Clark, David J. Adams, Emily R. Augustin, Yolanda Byrne, Rachel L. Cocozza, Michael Cubas-Atienzar, Ana I. Cuevas, Luis E. Cusinato, Martina
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Published in
Emerging Infectious Diseases
We investigated the dynamics of seroconversion in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. During March 29–May 22, 2020, we collected serum samples and associated clinical data from 177 persons in London, UK, who had SARS-CoV-2 infection. We measured IgG against SARS-CoV-2 and compared antibody levels with patient out...
Fang, Ferric C Naccache, Samia N Greninger, Alexander L
Published in
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Diagnostic testing has played and will continue to play a major role in the coronavirus disease 2019 (COVID-19) pandemic. The ability to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in respiratory secretions is essential to determine when an individual is infected and potentially infectious to others. Viral detection is used ...
Root, Heather Boyce, Ross Robinson, Whitney R
Published in
BMJ Global Health