Zhao, Xiujuan Li, Yonghao Ma, Wei Lian, Ping Yu, Xiling Chen, Shida Huang, Xia Liu, Bingqian Lu, Lin
Published in
The British journal of ophthalmology
To compare the efficacy of macular buckling (MB) and pars plana vitrectomy (PPV) for full-thickness macular holes (FTMH) and associated macular detachment (MD) in highly myopic eyes. Prospective interventional case series of eyes undergoing PPV or MB for FTMH and MD. Best-corrected visual acuity (BCVA) at postoperative month 24. Other measured outc...
Zheng, Feihui Chua, Jacqueline Ke, Mengyuan Tan, Bingyao Yu, Marco Hu, Qinglan Cheung, Chui Ming Gemmy Ang, Marcus Lee, Shu Yen Wong, Tien Yin
...
Published in
The British journal of ophthalmology
To quantify retinal and choriocapillaris (CC) microvasculature in highly myopic (HM) eyes with myopic macular degeneration (MMD) using swept-source optical coherence tomography angiography (SS-OCTA). 162 HM eyes (spherical equivalent ≤ -6.0 dioptres or axial length (AL) ≥26.5 mm) from 98 participants were enrolled, including 60 eyes (37.0%) with te...
Gallo, Beatrice de Silva, Samantha R Mahroo, Omar A Saihan, Zubin Patel, Praveen J Dowler, Jonathan G Pavesio, Carlos Keane, Pearse A Tufail, Adnan Sagoo, Mandeep S
...
Published in
The British journal of ophthalmology
To describe clinical and multimodal imaging features in a cohort of choroidal macrovessels. Demographics and multimodal imaging features of 16 eyes of 13 patients with choroidal macrovessels were reviewed. The multimodal imaging included colour fundus photography, fundus autofluorescence (FAF), spectral domain enhanced depth imaging optical coheren...
Shen, Liangbo L Sun, Mengyuan Ahluwalia, Aneesha Park, Michael M Young, Benjamin K Lad, Eleonora M Toth, Cynthia Del Priore, Lucian V
Published in
The British journal of ophthalmology
The macular central 1 mm diameter zone is crucial to patients' visual acuity, but the long-term natural history of central sparing in eyes with geographic atrophy (GA) is unknown. We manually segmented GA in 210 eyes with GA involving central 1 mm diameter zone (mean follow-up=3.8 years) in the Age-Related Eye Disease Study. We measured the residua...
Gan, Yuhong Zhang, Xiongze Su, Yongyue Shen, Mei Peng, Yuting Wen, Feng
Published in
The British journal of ophthalmology
To compare the sensitivity and specificity of identifying and evaluating the choroidal neovascularisation (CNV) in punctate inner choroidopathy (PIC) by optical coherence tomography angiography (OCTA) versus dye angiography. Consecutive patients diagnosed with PIC were enrolled in this study from June 2016 to December 2019. During the same visit, e...
Pamplona, Daniela Hilgen, Gerrit Hennig, Matthias Cessac, Bruno Sernagor, Evelyne Kornprobst, Pierre
One primary goal in analyzing sensory neurons’ recordings is to map the sensory space to the neural response, thus estimating the neuron’s receptive fields (RFs). For visual neurons, the classical method to estimate RFs is the Spike Triggered Average (STA). In short, STA consistsestimate the average stimulus before each spike evoked by a white nois...
Laing, Steven T Tassew, Nardos Tesar, Devin Wang, Yue Crowell, Susan R Gray, Julia Kwong, Mandy Loyet, Kelly M Andaya, Roxanne Kusi, Aija
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Published in
Toxicologic pathology
Fusion of biologic therapeutics to hyaluronic acid binding proteins, such as the link domain (LD) of Tumor necrosis factor (TNF)-Stimulated Gene-6 (TSG-6), is expected to increase vitreous residence time following intravitreal injection and provide for long-acting delivery. The toxicity of a single intravitreal dose of free TSG-6-LD and fusion prot...
Filippatou, Angeliki G Vasileiou, Eleni S He, Yufan Fitzgerald, Kathryn C Kalaitzidis, Grigorios Lambe, Jeffrey Mealy, Maureen A Levy, Michael Liu, Yihao Prince, Jerry L
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Published in
Multiple sclerosis (Houndmills, Basingstoke, England)
Prior studies have suggested that subclinical retinal abnormalities may be present in aquaporin-4 immunoglobulin G (AQP4-IgG) seropositive neuromyelitis optica spectrum disorder (NMOSD), in the absence of a clinical history of optic neuritis (ON). Our aim was to compare retinal layer thicknesses at the fovea and surrounding macula between AQP4-IgG+...
Rougier, Marie-Benedicte Gattoussi, Sarra Le-Goff, Melanie Korobelnik, Jean Francois
Published in
European journal of ophthalmology
In non-arteritic anterior ischemic optic neuropathy (NAION), optical coherence tomography angiography (OCTA) shows changes in peripapillary vascularization. However, the presence of an optic disc edema may induce artifacts that prevent visualizing the peripapillary network. The aim of this study was to evaluate the peripapillary vascularization in ...
Son, Taeyoon Kim, Tae-Hoon Ma, Guangying Kim, Hoonsup Yao, Xincheng
Published in
Experimental biology and medicine (Maywood, N.J.)
Functional mapping of photoreceptor physiology is important for better disease diagnosis and treatment assessment. Fast intrinsic optical signal (IOS), which arises before light-evoked pupillary response, promises a unique biomarker of photoreceptor physiology for objective optoretinography with high resolution. This study is to test the feasibilit...
