Since the Rio Convention in 1992, there has been a strong political and ethical imperative to link biodiversity conservation and equity and to promote gender-sensitive policies. However, there has also been a huge gap between these global injunctions and local actions. Mangrove conservation policy is a good illustration of "nature grabbing," which ...
Acute myeloid leukemias are a group of hematological malignancies characterized by a poor prognosis for survival. The discovery of oncogenic mutations in the FMS-like tyrosine kinase 3 (FLT3) gene has led to the development of tyrosine kinase inhibitors such as quizartinib. However, achieving complete remission in patients remains challenging becau...
Published in Frontiers in Microbiology
The successful evolution of KPC-2 in bacteria has limited the clinical practice of carbapenems. This dilemma deteriorated the prognosis of associated infections and hence attracted increasing attention from researchers to explore alternative therapeutic options. Here, the enzyme inhibition assay was first performed to screen for a potent KPC-2 inhi...
Published in Frontiers in Immunology
Background The majority of patients with lung cancer exhibit drug resistance after anti-PD-1 immunotherapy, leading to shortened patient survival time. Previous studies have suggested an association between epigenetic abnormalities such as methylation and clinical response to anti-PD-1 immunotherapy, while the role of SUMOylation in resistance to a...
Published in Frontiers in Physiology
Isometric resistance training (IRT) has emerged as an efficacious therapeutic intervention to reduce ambulatory blood pressure (BP), and BP diurnal variability. However, once the required decreases in BP have been achieved the efficacy of implementing a reduced maintenance dose is not understood. Therefore, the purpose of this study was to determin...
Published in Frontiers in Plant Science
Phytophthora cinnamomi Rands devastates forest species worldwide, causing significant ecological and economic impacts. The European chestnut (Castanea sativa) is susceptible to this hemibiotrophic oomycete, whereas the Asian chestnuts (Castanea crenata and Castanea mollissima) are resistant and have been successfully used as resistance donors in br...
Published in Frontiers in Medicine
Streptococcus is one of the common pathogens of suppurative infections. Invasive group A Streptococcus (iGAS) infections often develop from skin or soft tissue infections, and streptococcal toxic shock syndrome is considered the main cause of death in Chinese children with iGAS infectious disease. However, soft tissue infections caused by iGAS infe...
Published in Frontiers in Tropical Diseases
Background Neonicotinoids are gradually being introduced into malaria vector control due to their mode of action that targets insect nicotinic acetylcholine receptors (nAChRs). However, prior to scaling up novel insecticides, it is important to assess the susceptibility of the mosquito population to this molecule. The present study aimed to determi...
Published in Zeitschrift für Angewandte Linguistik
Resistance in the ‚Third Reich‘ was a mostly solitary and thus lonely struggle not only against the National Socialist regime, but also for being heard by the silent majority society. In addition to the various communicative practices of warning, admonishing, or calls to action, argumentation also played an important role. The task was not only to ...
Published in Frontiers in Agronomy
The Hessian fly (HF, Mayetiola destructor) is one of the most destructive pests of wheat and wheat-related cereals. Wheat resistance and/or susceptibility to HF are often affected by the levels of phytohormones in plants. In this study, we tested the impact of phytohormones on Molly wheat resistance to HF biotype GP by externally applying phytohorm...
