Although conceptually attractive, the use of ensemble data assimilation methods, such as the ensemble Kalman filter (EnKF), can be constrained by intensive computational requirements. In such cases, the ensemble optimal interpolation scheme (EnOI), which works on a single model run instead of ensemble evolution, may offer a sub-optimal alternative....
Published in Bibliotheksdienst
Unter Federführung der Zürcher Hochschule für Angewandte Wissenschaften (ZHAW) wurde eine zentrale Plattform für Open Educational Resources (OER) für die Schweizer Hochschullandschaft entwickelt, um die Verbreitung von offenen Lehrmaterialien zu erleichtern. Die Plattform basiert auf der Software Edu-Sharing und wurde in Zusammenarbeit mit anderen ...
Published in JMIR formative research
The COVID-19 pandemic sparked a surge of research publications spanning epidemiology, basic science, and clinical science. Thanks to the digital revolution, large data sets are now accessible, which also enables real-time epidemic tracking. However, despite this, academic faculty and their trainees have been struggling to access comprehensive clini...
In the rapidly evolving landscape of scientific research, the proliferation of ontologies and semantic artefacts necessitates the development of robust systems to manage and utilise these resources effectively. Semantic Artefact Catalogues (SAC) and ontology repositories are critical in this regard, especially within the framework of the European O...
Published in Frontiers in Political Science
The aim of this article is to highlight and conceptualize key aspects of social closures that impact the German nuclear waste management case. According to the German legislator, the public must be involved in the search for a final repository for high-level radioactive waste. De facto, however, almost the entire population of Germany is excluded. ...
The reuse of paediatric individual patient data (IPD) from clinical trials (CTs) is essential to overcome specific ethical, regulatory, methodological, and economic issues that hinder the progress of paediatric research. Sharing data through repositories enables the aggregation and dissemination of clinical information, fosters collaboration betwee...
Published in Alzheimer's & dementia : the journal of the Alzheimer's Association
Individuals with Down syndrome (DS) have a partial or complete trisomy of chromosome 21, resulting in an increased risk for early-onset Alzheimer's disease (AD)-type dementia by early midlife. Despite ongoing clinical trials to treat late-onset AD, individuals with DS are often excluded. Furthermore, timely diagnosis or management is often not avai...
Individuals with Down syndrome (DS) have a partial or complete trisomy of chromosome 21, resulting in an increased risk for early-onset Alzheimer's disease (AD)-type dementia by early midlife. Despite ongoing clinical trials to treat late-onset AD, individuals with DS are often excluded. Furthermore, timely diagnosis or management is often not avai...
