Cette note de recherche documente l’influence de l’État central dans l’orientation géographique des investissements immobiliers. Depuis 2009, les aides fiscales à l’investissement locatif des ménages (actuel dispositif Pinel) ne sont disponibles que sur une part de plus en plus restreinte du territoire national. Le recul des périmètres d’éligibilit...
Published in Frontiers in Toxicology
Published in Frontiers in Chemical Biology
Introduction: Dual specific phosphatases (DUSPs) are mitogen-activated protein kinase (MAPK) regulators, which also serve as drug targets for treating various vascular diseases. Previously, we have presented mechanistic characterizations of DUSP5 and its interaction with pERK, proposing a dual active site. Methods: Herein, we characterize the inter...
Published in Frontiers in Medicine
Introduction This study investigates the complexity of regulatory affairs in the medical device industry, a critical factor influencing market access and patient care. Methods Through qualitative research, we sought expert insights to understand the factors contributing to this complexity. The study involved semi-structured interviews with 28 profe...
Published in Frontiers in Communication
Disinformation generates political polarization and affects the quality of democracy, so understanding attitudes towards the regulation of disinformation will help society and its leaders to develop effective and inclusive approaches to combat this phenomenon. The purpose of the research is to determine the perceptions and propensities of Andean Co...
ABSTRACT Polyamines have vital functions in organisms, including bacteria, plants, and animals, with key roles in growth, development, and stress responses. Spermine/spermidine N 1-acetyl transferases (SSATs) regulate polyamine abundance by catalysing their N -acetylation, thereby reducing the pool of polyamines and producing other bioactive compon...
Plants take up metals, including essential micronutrients [iron (Fe), copper (Cu), zinc (Zn), and manganese (Mn)] and the toxic heavy metal cadmium (Cd), from soil and accumulate these metals in their edible parts, which are direct and indirect intake sources for humans. Multiple transporters belonging to different families are required to transpor...
Published in Frontiers in Endocrinology
Published in Frontiers in Medicine
Background Falsified medicines and their international regulation impacts all healthcare sectors and their actors. These regulations aim to strengthen and protect the global pharmaceutical supply chain against falsified medicines. However, an evaluation of the impacts of these regulations on key stakeholders within the legitimate supply chain have ...
As a leader in social media, communications, digital humanities, and social science research globally, the Digital Media Research Centre (DMRC) welcomes the opportunity to make this submission to the Joint Select Committee on Social Media and Australian Society.
Our submission is detailed and extensive: our investment in this contribution reflects t...
