Jones, Siana Tillin, Therese Williams, Suzanne Rapala, Alicja Chaturvedi, Nishi Hughes, Alun D.
Published in
Frontiers in Physiology
Measuring local haemodynamics in skeletal muscle has the potential to provide valuable insight into the oxygen delivery to tissue, especially during high demand situations such as exercise. The aim of this study was to compare the skeletal muscle microvascular response during post-occlusive reactive hyperaemia (PORH) with the response to exercise, ...
D'Agata, Michele N Hoopes, Elissa K Berube, Felicia R Hirt, Alexandra E Witman, Melissa A
Published in
Experimental physiology
What is the central question of this study? Is there a racial disparity in macrovascular and/or microvascular function between young black and white women? What is the main finding and its importance? Black women (BLW) demonstrated impaired microvascular function but similar macrovascular function compared to white women (WHW). These findings sugge...
Young, Grace Marie Krastins, Digby Chang, David Lam, Jeng Quah, Jing Stanton, Tony Russell, Fraser Greaves, Kim Kriel, Yuri Askew, Christopher David
...
Published in
Experimental physiology
What is the central question of the study? Cuff-occlusion duration may influence contrast-enhanced ultrasound (CEUS) assessments of skeletal muscle microvascular blood flow responsiveness: what are the effects of 1, 3 and 5 min cuff-occlusion on the magnitude and reliability of calf muscle microvascular blood flow responsiveness in older adults? Wh...
Engelland, Rachel E Hemingway, Holden W Tomasco, Olivia G Olivencia-Yurvati, Albert H Romero, Steven A
Published in
Experimental physiology
• What is the central question of this study? What is the effect of lower leg hot water immersion on vascular ischaemia-reperfusion injury induced in the arm of young healthy humans? • What is the main finding and its importance? Lower leg hot water immersion successfully protects against vascular ischaemia-reperfusion injury in humans. This raises...
Kazune, Sigita Piebalga, Anda Strike, Eva Vanags, Indulis
Published in
Archives of Medical Sciences. Atherosclerotic Diseases
Introduction Vascular dysfunction due to reduced nitric oxide bioavailability plays an important role in the pathogenesis of sepsis. This meta-analysis examines evidence from published literature to evaluate whether in the adult population the presence/severity of sepsis is associated with impaired vasoreactivity. Material and methods We performed ...
Bisconti, Angela Valentina Cè, Emiliano Longo, Stefano Venturelli, Massimo Coratella, Giuseppe Shokohyar, Sheida Ghahremani, Reza Rampichini, Susanna Limonta, Eloisa Esposito, Fabio
...
Published in
Frontiers in Physiology
Vascular endothelial function is a strong marker of cardiovascular health and it refers to the ability of the body to maintain the homeostasis of vascular tone. The endothelial cells react to mechanical and chemical stimuli modulating the smooth muscle cells relaxation. The extent of the induced vasodilation depends on the magnitude of the stimulus...
Tusa, Anna-Boróka Magdás, Annamária Tusa, Réka-Júlia Incze, Al.
Published in
Internal Medicine
Objective. In lower limb peripheral artery disease the most commonly used method for the assessment of the main arterial system is represented by the determination of ankle-brachial index (ABI). The post-occlusive reactive hyperaemia (PORH) is a controversial method used for the evaluation of primary collateral circulation. The follow-up of these p...
Davidson, Sean M He, Zhenhe Dyson, Alex Bromage, Daniel I Yellon, Derek M
Published in
Journal of cellular and molecular medicine
Whether oxygen should be administered acutely during ST-segment elevation myocardial infarction is debated. Despite this controversy, the possible influence of supplementary oxygen on animal models of ischaemia-reperfusion injury or cardioprotection is rarely considered. We used an in vivo mouse model of ischaemia and reperfusion to investigate the...
Prakash, Kiran Chandran, Dinu S Khadgawat, Rajesh Jaryal, Ashok Kumar Deepak, Kishore K
Published in
Diabetes & vascular disease research
Insulin resistance is associated with endothelial dysfunction in type 2 diabetes mellitus, which can lead to impaired vascular reactivities of both systemic and cerebral circulations. Appropriate 'correction' of vascular reactivity results for non-endothelium-dependent systemic effects avoids misinterpretation of endothelial function. Therefore, we...
Rasool, Aida Hanum Ghulam Abdul Rahman, Aisyah Syairah Abd Ghaffar, Nor Aliza Nik Mahmood, Nik Mohd Zaki Wong, Abd Rahim
Published in
The Malaysian journal of medical sciences : MJMS
Post-occlusive skin reactive hyperaemia (PORH) is a model used to assess microvascular reactivity. This study aims to compare PORH response among pregnant hypercholesterolaemic patients with age and gestational age-matched controls. This cross sectional study involved 17 hypercholesterolaemic, pregnant women and 20 pregnant controls entering their ...
