Wang, Zhixin Fu, Rao Zhu, Na Wang, Junqi Zhang, Xiaorui Huang, Xiulan Li, Zhiyong
Published in
Phytochemical analysis : PCA
As a folk herbal medicine, Trillium tschonoskii has been used for thousands of years. However, due to the complexity of the chemical constituents of this herb, few investigations have acquired a comprehensive understanding of its quality markers. This study was conducted to characterise the chemical composition of T. tschonoskii and identify its po...
Wei, Yongheng Nie, Lei Gao, Lele Zhong, Liang Sun, Zhongyu Yang, Xiangchun Yue, Jianan Zeng, Yingzi Li, Lian Sun, Jing
...
Published in
Frontiers in Pharmacology
Xinkeshu tablets (XKST), a traditional Chinese patent medicine (CPM), have served in the clinical treatment of cardiovascular diseases (CVDs) for decades. However, its pharmacodyamic material basis was still unclear, and the holistic quality control has not been well established due to the lack of systematic research on the quality markers. In this...
Li, Taiping Wu, Fangfang Zhang, Aihua Dong, Hui Ullah, Ihsan Lin, Hao Miao, Jianhua Sun, Hui Han, Ying He, Yanmei
...
Published in
Frontiers in Pharmacology
Wutou decoction (WTD) is a traditional Chinese medicine prescription for the treatment of rheumatoid arthritis (RA), and this study systematically analyzed the metabolic mechanism and key pharmacodynamic components of WTD in RA rats by combining untargeted metabolomics and serum pharmacochemistry of traditional Chinese medicine to enrich the eviden...
Chen, Jingbin Song, Yonggui Zhou, Mingyue Yang, Ming Zhang, Ling Naeem, Abid Li, Zexie Deng, Yaqiong Liu, Yali Ai, Zhifu
...
Published in
Journal of separation science
Callerya nitida var. hirsutissima. Z.Wei is a classical, traditional Chinese herbal medicine mostly used to treat rheumatoid arthritis. Recent reports suggest that inconsistent and poor-quality control levels have primarily affected the therapeutic efficacy. Therefore, the aim of the current study was to investigate the active chemical ingredients,...
Zhang, Ming Wang, You-Wen Zhu, Yuan-Zhang Gu, Xiao-Ling
Published in
Biomedical chromatography : BMC
Burdock root is the root of Arctium lappa L., a plant of the Compositae family, which has the effects of dispersing wind and heat, detoxifying and reducing swelling. In order to better control the quality of burdock root, a screening study of quality control indicators was carried out. The current research combines biological activity evaluation wi...
Soliman, Alaa Bahaa Eldeen Pawluk, Shane Ashley Wilby, Kyle John Rachid, Ousama
Published in
Journal of clinical pharmacy and therapeutics
Robust critical appraisal tools for clinical pharmacokinetic studies are limited. Before development of such a tool is possible, quality markers (items deemed important for credibility of study results) must be identified. We aim to create an inventory of quality markers intended for the appraisal of clinical pharmacokinetic studies and to categori...
Chang, Xiangwei Zhang, Zhenyu Yan, Hui Su, Shulan Wei, Dandan Guo, Sheng Shang, Erxin Sun, Xiaodong Gui, Shuangying Duan, Jinao
...
Published in
Frontiers in Chemistry
Nucleobases, nucleosides, nucleotides and amino acids, as crucial nutrient compositions, play essential roles in determining the flavor, function and quality of Chrysanthemi Flos. The quality of Chrysanthemi Flos from different geographical origins is uneven, but there have been no reports about the screening of their quality markers based on nutri...
Frontiers Production Office,
Published in
Frontiers in Pharmacology
Dong, Rong Tian, Qingping Shi, Yongping Chen, Shanjun Zhang, Yougang Deng, Zhipeng Wang, Xiaojing Yao, Qingqiang Han, Liwen
Published in
Frontiers in Pharmacology
Background: Gardenia Fructus (GF), a traditional Chinese medicine of Gardenia Ellis in Rubiaceae family, has the potential to clear heat and purge fire and has been widely used to treat multiple infection-related diseases. However, the quality markers (Q-Markers) of GF have not been revealed comprehensively. Methods: In this experiment, the transge...
Wang, Yi-Kun Zhou, Zi-Meng Dai, Man-Yun Ma, Xiao-Fang Xiao, Xue-Rong Zhang, Shou-Wen Liu, Hong-Ning Li, Fei
Published in
Journal of separation science
Fructus Aurantii is a traditional medicated diet in East Asia. To determine the underlying chemical markers responsible for the quality and efficacy of Fructus Aurantii, a sensitive metabolomic method was applied to distinguish Fructus Aurantii in Jiangxi Province from other two geographical locations (Hunan Province and Chongqing City) in China. I...
